97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
99久久无码一区人妻A片蜜臀 ,欧洲人免费视频网站在线,5252av我爱haose0在线
首頁 > 產品中心 > 一抗 > 產品信息
SHBG Rabbit pAb (bs-1175R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-1175R
英文名稱 SHBG Rabbit pAb
中文名稱 性激素結合球蛋白抗體
別    名 Sex Hormone Binding Globulin; ABP; Androgen binding protein; MGC126834; MGC138391; SBP; Sex steroid binding protein; SHBG; TEBG; Testis specific androgen binding protein; Testosterone binding beta globulin; Testosterone Estradiol Binding Globulin; Testosterone estrogen binding globulin; SHBG_HUMAN; Sex hormone-binding globulin; Sex steroid-binding protein; Testis-specific androgen-binding protein; Testosterone-estradiol-binding globulin; TeBG; Testosterone-estrogen-binding globulin.  
Specific References  (2)     |     bs-1175R has been referenced in 2 publications.
[IF=7.31] Longfei Xiao. et al. Curcumin Ameliorates Age-Induced Tight Junction Impaired in Porcine Sertoli Cells by Inactivating the NLRP3 Inflammasome through the AMPK/SIRT3/SOD2/mtROS Signaling Pathway. OXID MED CELL LONGEV. 2023;2023:1708251  IF ;  Pig.  
[IF=4.292] Longfei Xiao. et al. Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cells. J Steroid Biochem. 2022 Feb;216:106041  IF ;  Dog.  
研究領域 腫瘤  生長因子和激素  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat (predicted: Rabbit,Cow,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 44 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SHBG: 301-402/402 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Sex hormone binding globulin (SHBG) is a glycoprotein synthesized by the liver. Circulating androgen and estrogen concentrations influence SHBG synthesis. Elevated testosterone, for example, causes SHBG synthesis to decrease, whereas high estrogen stimulates SHBG production. The regulation of SHBG synthesis, combined with SHBG's higher affinity for testosterone, impacts bioavailable testosterone levels. SHBG binds up to 98 percent of the steroid hormones in the blood including 5a-dihydrotestosterone (DHT), testosterone and androstenediol with particularly high affinity, and estradiol and estrone with slightly lower affinity.

Function:
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.

Subunit:
Homodimer.

Subcellular Location:
Secreted . Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

Tissue Specificity:
Isoform 1 and isoform 2 are present in liver and testis.

Post-translational modifications:
Variant Asn-356 contains one N-linked (GlcNAc...) at position 356.

Similarity:
Contains 2 laminin G-like domains.

SWISS:
P04278

Gene ID:
6462

Database links:

Entrez Gene: 404182 Cow

Entrez Gene: 6462 Human

Omim: 182205 Human

SwissProt: P04278 Human

Unigene: 632235 Human



性激素結合球蛋白(SHBG),又稱睪酮—雌二醇結合球蛋白。
SHBG是一運輸性激素的載體,它在性激素人作用過程中以及在各種生理病理情況下都有一定的變化和意義。
SHBG是由母體肝臟產生的循環類固醇類結合球蛋白,執行載體蛋白的功能,胰島素是肝臟合成SHBG的強大的抑制因子,胰島素抑制效應的主要作用點在于競爭性刺激肝臟SHBG的產生,因而SHBG減少是高胰島素血癥、胰島素抵抗的標志。
產品圖片
Tissue/cell: rat uterus tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-SHBG Polyclonal Antibody, Unconjugated(bs-1175R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产精品短视频 | 国产日产亚洲精华av | 理论片一级片 | 国产片在线观看 | 国产一区三区三区 | 黄色a一级 | 97视频久久 | 国产午夜av秒播在线观看 | 美女扒开腿让男人桶爽网站 | 91视频在线观看免费 | 天堂资源在线观看免费高清视频 | 午夜剧场成年 | 亚洲视频在线观看 | 中文不卡视频 | 国产精品久久久久久人妻精品 | 成人午夜爽爽爽免费视频 | 天天草夜夜骑 | 亚洲一区二区制服在线 | 国产欧美精品在线观看 | 成全影视在线观看第6季 | 深夜免费观看视频 | 91精品国产日韩一区二区三区 | 人妻无码中文字幕永久在线 | 无码人妻丰满熟妇区a?v | 日韩射吧 | 黄色网站视频在线 | avtom影院 | 国产一区二区精品久 | 很黄的网站在线观看 | 亚洲精品久久久久69影院 | 久久久久国色AⅤ免费看 | 欧美三日本三级少妇三级99观看视频 | 国产免费人成视频网站在线18 | 中文理论片 | 亚洲综合视频网站 | 久久婷婷人人澡人人爽人人爱 | 日韩久久精品 | 受被攻c哭高h视频在线观看 | 中国性感美女一级黄色影片 | 女主播扒开屁股给粉丝看尿口 | 国产亚洲精品美女久久久久久久久久 |