97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
制服丝袜人妻中文字幕在线,亚洲成人免费在线播放,欧亚一级片
首頁 > 產品中心 > 一抗 > 產品信息
IL-4 Rabbit pAb (bs-1740R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-1740R
英文名稱 IL-4 Rabbit pAb
中文名稱 白介素4抗體
別    名 B cell growth factor 1; B cell IgG differentiation factor; B Cell Stimulatory Factor 1; BCGF 1; BCGF1; Binetrakin; BSF 1; BSF1; HCGF; Hodgkin’s Cell Growth Factor; IA Inducing Factor; IGG1 induction factor; IL 4; Il4e12; Interleukin 4; Interleukin 4, isoform 1; Interleukin4; Lymphocyte stimulatory factor 1; Macrophage fusion factor; Mast cell growth factor 2; MCGF2; MFF; MGC79402; Pitrakinra; T cell growth factor 2; TCGF2; IL4_HUMAN; Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1.  
Specific References  (1)     |     bs-1740R has been referenced in 1 publications.
[IF=1.813] Jiang Yan. et al. Exploring the Mechanism of Berberine Intervention in Ulcerative Colitis from the Perspective of Inflammation and Immunity Based on Systemic Pharmacology. Evid-Based Compl Alt. 2021;2021:9970240  IHC ;  Rat.  
研究領域 腫瘤  免疫學  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 14 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-4: 25-125/137 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation. This cytokine has been reported to promote resolution of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has an essential role in the production of allergen-specific immunoglobin (Ig) E. This pro-inflammatory cytokine has been observed to be increased in COVID-19 (Coronavirus disease 2019) patients, but is not necessarily associated with severe COVID-19 pathology. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020]

Function:
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.

Subcellular Location:
Secreted.

DISEASE:
Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.

Similarity:
Belongs to the IL-4/IL-13 family.

SWISS:
P05112

Gene ID:
3565

Database links:

Entrez Gene: 3565 Human

Entrez Gene: 16189 Mouse

Omim: 147780 Human

SwissProt: P05112 Human

SwissProt: P07750 Mouse

Unigene: 73917 Human

Unigene: 276360 Mouse




白介素-4僅限于活化T細胞,肥大細胞和噬堿性白細胞。
IL-4對各種淋巴細胞,單核—巨噬細胞,甚至纖維母細胞和上皮細胞都有促生長和分化的作用。
產品圖片
Sample: Lane 1: THP-1 (Human) Cell Lysate at 30 ug Primary: Anti-IL-4 (bs-1740R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 17 kD Observed band size: 16 kD
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 在线看片成人 | 日韩黄色一级片 | 日日影视 | 久久一级黄色片 | yellow高清免费观看日本 | 爽爽免费视频 | 成人勉费视频 | 内射女校花一区二区三区 | 狠狠做深爱婷婷久久综合一区 | 国产精品无码免费视频二三区 | 天天插夜夜骑 | 完全着衣の爆乳お姉さんが | 男同男性xx视频在线观看免费 | 欧美国产精品日韩在线 | 久久久久偷看国产亚洲87 | 日韩精品人妻系列无码AV东京 | 男女久久久国产一区二区三区 | 亚洲91av | 亚洲最新在线视频 | 女人下边被添全过程A片 | 99在线在线视频免费视频观看 | 外企女老板被洋老外啪啪 | 亚洲自偷自偷图片 | 好男人社区神马影视www | 欧洲免费无线码在线一区 | 午夜影院一区二区 | 天天曰夜夜操 | 午夜视频在线看 | 日韩视频一区在线观看 | 欧美肥臀大屁股MAGNET | 最近的2019中文字幕免费 | 香蕉精品视频在线观看 | 日韩精品无码视频免费专区 | 天天插天天爱 | aaa日本高清在线播放免费观看 | 久久精品亚洲成在人线av麻豆 | 国内毛片久久 | 91在线免费看| 国产日产欧产美韩毛毛片 | 伦理片一级片 | 91性视频 |