97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
天天综合天天操,成年女人WWXX免费国产,国产精品久久久久久人妻黑料
首頁 > 產品中心 > 一抗 > 產品信息
RPH3AL Rabbit pAb (bs-4183R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-4183R
英文名稱 RPH3AL Rabbit pAb
中文名稱 Ras相關GTP結合蛋白抗體
別    名 Noc2; Rab effector Noc2; Rabphilin 3A-like(without C2 domains); Rabphilin 3A-like; Rabphilin-3A-like protein; RPH3AL; RPH3L_HUMAN; No C2 domains protein; Gm1753.  
研究領域 腫瘤  免疫學  信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Cow,Chicken,Dog)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RPH3AL: 25-130/315 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Rabphilin-3AL (rabphilin-3A-like), also known as RPH3AL or NOC2, is a cytoplasmic Rab GTPase effector. It contains one FYVE-type zinc finger and one Rab-binding (RBD) domain, but unlike its related protein, rabphilin-3A, rabphilin-3AL does not contain any C2 domains. Rabphilin-3AL is expressed in a variety of tissues, with highest levels found in kidney, skeletal muscle, pancreas, liver, ovary, stomach, heart and thyroid. It is believed to play a role regulating calcium-dependent secretory vesicle exocytosis in endocrine and exocrine cells. Via its RBD domain, rabphilin-3AL is capable of binding Rab 27a and, through this interaction, rabphilin-3AL is recruited to dense-core vesicles. With lower affinity, rabphilin-3AL can also bind Rab 3 and Rab 8 with its RBD domain. Through an interaction with Rab 3, rabphilin-3AL can inhibit G-protein signaling in endocrine pancreas and positively regulate insulin secretion. Rabphilin-3AL knockout mice display accumulation of secretory granules and irregular shape in exocrine cells.

Function:
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.

Subunit:
Recruited to dense-core vesicles through specific interaction with RAB27A in endocrine cells. Interacts with RAB3A, RAB3B, RAB3C and RAB3D. Interacts with ZYX.

Subcellular Location:
Cytoplasm. Cytoplasmic vesicle, secretory vesicle membrane. Recruited to the vesicle membrane in a GTP-and RAB3B-dependent manner in epithelial cells.

Tissue Specificity:
Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.

Similarity:
Contains 1 FYVE-type zinc finger.
Contains 1 RabBD (Rab-binding) domain.

SWISS:
Q9UNE2

Gene ID:
9501

Database links:

Entrez Gene: 9501 Human

Omim: 604881 Human

SwissProt: Q9UNE2 Human

Unigene: 651925 Human



產品圖片
Sample: Ovary (Mouse) Lysate at 40 ug Primary: Anti-RPH3AL (bs-4183R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kD Observed band size: 34 kD
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲人亚洲人色久 | 丰满人妻跪趴高撅肥臀 | 永久免费精品影视网站播放器 | 中文字幕视频一区二区三区久 | 亚洲国产精品成人无码区 | 亚洲色大情网站WWW 国产99视频精品免费观看6 | 国产欧美视频一区二区三区 | 精品国内二区三区 | 亚洲精品中文字幕在线观看 | 美女一区二区久久 | 97精品伊人久久久大香线蕉 | 国产首页天堂在线 | 国内精品人妻无码久久久影院蜜桃 | 性色aⅤ极品无码专区亚洲 成人水多啪啪片 | 亚洲韩国精品无码一区二区三区 | 日本精品一区 | 93超碰国产大屁股 | 俺去啦久久草在线视频 | 国产区精品一区二区不卡中文 | 野花社区www官网在线观看 | 无码国产69精品久久久久 | 五月天狠狠色 | 日韩黄色录相 | 男男GV白嫩小受GV在线播放 | 伊人久久视频在线 | 韩国av片女演员 | 最新日韩AV网址在线观看 | chaopeng视频 | 91精品久久久 | 国内精品免费久久久久软件 | 欧美《熟妇的荡欲》在线观看 | 亚洲资源网 | 恋夜久久 | 天地争霸美猴王在线观看 | 久草免费在线视频 | 美女国产一区 | 成年人中文字幕在线观看 | 亚洲一区二区三区不卡国产欧美 | 亚洲午夜福利在线观看老司机 | jizz国产精品网站 | 久久亚洲美女精品国产精品 |