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Hyaluronidase2 Rabbit pAb (bs-5888R)  
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50ul/1180.00元
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產品編號 bs-5888R
英文名稱 Hyaluronidase2 Rabbit pAb
中文名稱 透明質酸酶2/玻璃酸酶2抗體
別    名 Hyal 2; Hyal-2; Hyal2; HYAL2_HUMAN; Hyaluronidase 2; Hyaluronidase 2 Precursor; Hyaluronidase-2; Hyaluronoglucosaminidase 2; Hyaluronoglucosaminidase-2; LUCA 2; LUCA-2; LUCA2; Lung carcinoma protein 2; lysosomal hyaluronidase; PH 20 homolog.  
Specific References  (2)     |     bs-5888R has been referenced in 2 publications.
[IF=6.438] Anna Kocurkova. et al. Endogenously produced hyaluronan contributes to the regulation of peritoneal adhesion development. BIOFACTORS. 2023 May;:  IHC ;  Mouse.  
[IF=4.879] Petra ?ádníková. et al. The Degradation of Hyaluronan in the Skin. Biomolecules. 2022 Feb;12(2):251  WB,IHC,IF ;  Human.  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse (predicted: Rat)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 49 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HYAL2: 111-210/473 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.

Function:
Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.

Subunit:
Interacts with MST1R.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.

Tissue Specificity:
Widely expressed. No expression detected in adult brain.

Similarity:
Belongs to the glycosyl hydrolase 56 family.
Contains 1 EGF-like domain.

SWISS:
Q12891

Gene ID:
8692

Database links:

Entrez Gene: 8692 Human

Entrez Gene: 15587 Mouse

Entrez Gene: 404697 Pig

Entrez Gene: 64468 Rat

Omim: 603551 Human

SwissProt: Q12891 Human

SwissProt: O35632 Mouse

SwissProt: Q9Z2Q3 Rat

Unigene: 76873 Human

Unigene: 440982 Mouse

Unigene: 4834 Mouse

Unigene: 6149 Pig

Unigene: 8278 Rat



產品圖片
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-Hyaluronidase2 (bs-5888R) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution Predicted band size: 49 kD Observed band size: 49 kD
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Hyluronidase 2 Polyclonal Antibody, Unconjugated(bs-5888R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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