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RAB8B Rabbit pAb (bs-6168R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-6168R
英文名稱 RAB8B Rabbit pAb
中文名稱 ras癌基因家族RAB8B抗體
別    名 GTPase Rab8b; 5930437D16; FLJ38125; RAB 8b protein; RAB44; Rab8b; RAB8B, member RAS oncogene family; RAB8B_HUMAN; Ras-related protein Rab-8B.  
研究領域 腫瘤  細胞生物  染色質和核信號  信號轉導  G蛋白偶聯受體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Pig,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 23 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RAB8B: 21-120/207 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes

Function:
May be involved in vesicular trafficking and neurotransmitter release (By similarity). May participate in cell junction dynamics in Sertoli cells.

Subunit:
Interacts with OTOF and PEX5R (By similarity). Interacts with RAB3IP. Interacts with VIM AND CDH1 (By similarity). Associated with actin, delta-catenin and alpha and beta tubulins.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side

Similarity:
Belongs to the small GTPase superfamily. Rab family.

SWISS:
Q92930

Gene ID:
51762

Database links:

Entrez Gene: 51762 Human

Entrez Gene: 235442 Mouse

Entrez Gene: 266688 Rat

Omim: 613532 Human

SwissProt: Q92930 Human

SwissProt: P61028 Mouse

SwissProt: P70550 Rat

Unigene: 389733 Human

Unigene: 260376 Mouse

Unigene: 10995 Rat



產品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RAB8B) Polyclonal Antibody, Unconjugated (bs-6168R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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