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CRISP3 Rabbit pAb (bs-6521R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產(chǎn)品編號(hào) bs-6521R
英文名稱(chēng) CRISP3 Rabbit pAb
中文名稱(chēng) 富含半胱氨酸分泌蛋白3抗體
別    名 Aeg 2; Aeg2; CRIS3_HUMAN; CRISP 3; CRISP-3; Crisp3; CRS 3; CRS3; Cysteine rich secretory protein 3; Cysteine-rich secretory protein 3; SGP 28; SGP28; SGP28 protein; Specific granule protein(28 kDa); Specific granule protein of 28 kDa.  
Specific References  (1)     |     bs-6521R has been referenced in 1 publications.
[IF=2.532] Chenming Zhang. et al. Transcriptomics and proteomics analysis to explore the mechanism of Yishen Tongluo formula repairing sperm DNA damage in rats. ANDROLOGIA. 2022 Sep;:e14582  WB ;  Rat.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  腫瘤細(xì)胞生物標(biāo)志物  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 25 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CRISP3: 21-120/245 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. AEG is a sperm surface protein involved in the fusion of egg and sperm. Although CRISP-1 (also designated AEG-like protein, ARP, cysteine-rich secretory protein-1 or AEG-related protein) is not the ortholog of rodent AEG, it resembles AEG in that it is an epididymal secretory glycoprotein that binds to the postacrosomal region of the sperm head. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva. The gene that encodes CRISP-3 is an early response gene that may participate in the pathophysiology of the autoimmune lesions of Sjogren’s syndrome.

Subunit:
Interacts with A1BG.

Subcellular Location:
Secreted. In neutrophils, localized in specific granules.

Tissue Specificity:
Salivary gland, pancreas and prostate epididymis, ovary, thymus and colon.

Similarity:
Belongs to the CRISP family.

SWISS:
P54108

Gene ID:
10321

Database links:

Entrez Gene: 10321 Human

SwissProt: P54108 Human

Unigene: 404466 Human



產(chǎn)品圖片
Sample: Thymus (Mouse) Lysate at 40 ug Primary: Anti- CRISP3 (bs-6521R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 25 kD Observed band size: 29kD
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