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ICAM5 Rabbit pAb (bs-6686R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-6686R
英文名稱(chēng) ICAM5 Rabbit pAb
中文名稱(chēng) 細(xì)胞間粘附分子5抗體
別    名 ICAM5_HUMAN; ICAM5 precursor; Intercellular adhesion molecule 5; Intercellular adhesion molecule 5 precursor; Intercellular adhesion molecule 5, telencephalin; Telencephalin; TLCN; TLN.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  細(xì)胞粘附分子  細(xì)胞類(lèi)型標(biāo)志物  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse (predicted: Rat,Pig,Cow)
產(chǎn)品應(yīng)用 WB=1:500-2000,Flow-Cyt=0.2ug/test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 97 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ICAM5: 501-600/924 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

Function:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.

Similarity:
Belongs to the immunoglobulin superfamily. ICAM family.
Contains 9 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:
Q9UMF0

Gene ID:
7087

Database links:

Entrez Gene: 7087 Human

Entrez Gene: 15898 Mouse

Entrez Gene: 313785 Rat

Omim: 601852 Human

SwissProt: Q9UMF0 Human

SwissProt: Q60625 Mouse

Unigene: 465862 Human

Unigene: 59765 Rat



產(chǎn)品圖片
Sample: Hippocampus (Mouse) Lysate at 40 ug Primary: Anti- ICAM5 (bs-6686R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 97 kD Observed band size: 167 kD
Blank control: Hela. Primary Antibody (green line): Rabbit Anti-ICAM5 antibody (bs-6686R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 0.2μg /test. Protocol The cells were incubated in 5 %BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
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