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CCDC80 Rabbit pAb (bs-7992R)  
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產品編號 bs-7992R
英文名稱 CCDC80 Rabbit pAb
中文名稱 卷曲螺旋結構域蛋白80抗體
別    名 DRO1; okuribin; SSG1; steroid sensitive gene 1; steroid sensitive protein 1; CCD50; CCD80_HUMAN; CCDC80; CL2; Coiled coil domain containing 80; Coiled coil domain containing protein 50; Coiled-coil domain-containing protein 80; Down regulated by oncogenes protein 1; Down-regulated by oncogenes protein 1; Nuclear envelope protein okuribin; Protein Ymer; Up-regulated in BRS-3 deficient mouse homolog; URB.  
Specific References  (1)     |     bs-7992R has been referenced in 1 publications.
[IF=6.684] Jing Wang. et al. Coiled-Coil Domain Containing 80 Suppresses Nonylphenol-Induced Colorectal Cancer Cell Proliferation by Inhibiting the Activation of ERK1/2. Front Cell Dev Biol. 2021; 9: 759820  IHC ;  Human.  
研究領域 腫瘤  細胞生物  發育生物學  神經生物學  干細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Chicken,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 106 kDa
檢測分子量
細胞定位 細胞外基質 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CCDC80: 201-300/950 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Promotes cell adhesion and matrix assembly.
Tissue specificity: Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.

Function:
Promotes cell adhesion and matrix assembly (By similarity).

Subunit:
Binds to various extracellular matrix proteins (By similarity).

Subcellular Location:
Secreted, extracellular space, extracellular matrix (By similarity).

Tissue Specificity:
Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the CCDC80 family.

SWISS:
Q76M96

Gene ID:
151887

Database links:

Entrez Gene: 151887 Human

Entrez Gene: 67896 Mouse

Entrez Gene: 64387 Rat

SwissProt: Q76M96 Human

SwissProt: Q8R2G6 Mouse

SwissProt: Q6QD51 Rat

Unigene: 477128 Human

Unigene: 181074 Mouse

Unigene: 2193 Rat



產品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCDC80) Polyclonal Antibody, Unconjugated (bs-7992R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCDC80) Polyclonal Antibody, Unconjugated (bs-7992R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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