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ASMTY Rabbit pAb (bs-6961R)  
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產品編號 bs-6961R
英文名稱 ASMTY Rabbit pAb
中文名稱 松果體N甲基乙酰羥色胺抗體
別    名 acetylserotonin methyltransferase(Y chromosome); acetylserotonin N-methyltransferase; Acetylserotonin O-methyltransferase; ASMT; ASMTY; HIOM_HUMAN; HIOMT; HIOMTY; Hydroxyindole O-methyltransferase.  
Specific References  (6)     |     bs-6961R has been referenced in 6 publications.
[IF=5.249] Zhang, WL.. et al. Expression of arylalkylamine n-acetyltransferase (AANAT) and acetylserotonin o-methyltransferase (ASMT) in the corpus luteum of pregnant sows and synthesis of melatonin in luteal cells. 2021 Nov 24  WB,IHC ;  Pig.  
[IF=3.24] Herman, A. P., et al. "Central Interleukin-1β Suppresses the Nocturnal Secretion of Melatonin." Mediators of Inflammation 2016 (2016).  WB ;  Others.  
[IF=2.71] Herman, A. P., et al. "Interleukin-1β Modulates Melatonin Secretion in Ovine Pineal Gland: Ex Vivo Study." BioMed Research International (2015).  WB ;  Other Species.  
[IF=2.089] Huawei Wei. et al. Melatonin through blockade of Hif-1α signaling mediates the anti-fibrosis under hypoxia in canine Sertoli cells. REPROD BIOL. 2022 Dec;22:100677  WB, IHC ;  Dog.  
[IF=1.858] Wenbo Ge. et al. Melatonin protects sheep endometrial epithelial cells against lipopolysaccharide-induced inflammation in vitro. REPROD DOMEST ANIM. 2022 Aug;:  IHC ;  Sheep.  
[IF=0.86] Herman et al. Endotoxin-induced inflammation disturbs melatonin secretion in ewe. (2017) Asian-Australas.J.Anim.Sci. 30:1784-1795  WB ;  Sheep.  
研究領域 細胞生物  免疫學  神經生物學  內分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Rat (predicted: Human,Mouse,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 38 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Dopamine transporter: 241-345/345 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Most abundant in pineal gland, less in retina and brain, not in pigment epithelium.

Function:
Produces melatonin (N-acetyl-5-methoxytryptamine) from N-acetylserotonin.

Tissue Specificity:
Expressed in the pineal gland (at protein level). In the retina, very low expression is found at the mRNA level (PubMed:7989373), and not at the protein level (PubMed:8574683).

Similarity:
Belongs to the methyltransferase superfamily.

SWISS:
P46597

Gene ID:
438

Database links:
UniProtKB/Swiss-Prot: P46597.1

產品圖片
Sample: Brain (Rat) Lysate at 40 ug Primary: Anti- ASMTY (bs-6961R) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution Predicted band size: 38 kD Observed band size: 38/45 kD
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