97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
美女av在线免费,西西人体www大胆高清视频,JAPANESEHD熟女熟妇伦
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
TRPM7 Rabbit pAb (bs-9044R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-9044R
英文名稱 TRPM7 Rabbit pAb
中文名稱 瞬時(shí)受體電位離子通道蛋白7抗體(M亞家族)
別    名 CHAK 1; CHAK; CHAK1; Channel kinase 1; Channel-kinase 1; FLJ20117; FLJ25718; homolog of mouse transient receptor potential-phospholipase C-interacting kinase; Long transient receptor potential channel 7; LTRPC 7; LTRPC ion channel family member 7; LTrpC-7; LTRPC7; transient receptor potential cation channel subfamily M member 7; TRP PLIK; TRP-PLIK; TRPM 7; TRPM7; TRPM7_HUMAN.  
Specific References  (2)     |     bs-9044R has been referenced in 2 publications.
[IF=4.196] Takashina Y et al. Sodium Citrate Increases Expression and Flux of Mg Transport Carriers Mediated by Activation of MEK/ERK/c-Fos Pathway in Renal Tubular Epithelial Cells.(2018) Nutrients. Sep 20 ;10(10)  WB ;  Rat.  
[IF=2.26] Calik Muhammet. et al. Prognostic Value of TRPM7 Expression and Factor XIIIa-Expressing Tumor-Associated Macrophages in Gastric Cancer. Gastroent Res Pract. 2021;2021:7249726  IHC ;  Human.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 Flow-Cyt=1ug/Test,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 180, 205 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRPM7: 801-900/1865 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam.[provided by RefSeq, May 2010].

Function:
Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).

Subunit:
Homodimer. Interacts with PLCB1. Forms heterodimers with TRPM6.

Subcellular Location:
Membrane; Multi-pass membrane protein

Post-translational modifications:
Autophosphorylated (By similarity).

DISEASE:
Defects in TRPM7 are a cause of susceptibility to amyotrophic lateral sclerosis-parkinsonism/dementia complex type 1 (ALS-PDC1) [MIM:105500]; also called amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam or Guam disease. Amyotrophic lateral sclerosis-parkinsonism/dementia complex type 1 is a neurodegenerative disorder characterized by chronic, progressive and uniformly fatal amyotrophic lateral sclerosis and parkinsonism-dementia. Both diseases are known to occur in the same kindred, the same sibship and even the same individual.

Similarity:
In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
In the N-terminal section; belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM7 sub-subfamily.
Contains 1 alpha-type protein kinase domain.

SWISS:
Q96QT4

Gene ID:
54822

Database links:

Entrez Gene: 54822 Human

Entrez Gene: 58800 Mouse

Entrez Gene: 679906 Rat

Omim: 605692 Human

SwissProt: Q96QT4 Human

SwissProt: Q923J1 Mouse

SwissProt: Q925B3 Rat

Unigene: 512894 Human

Unigene: 244705 Mouse

Unigene: 86991 Rat



產(chǎn)品圖片
Blank control(black line):MCF-7. Primary Antibody (green line): Rabbit Anti-TRPM7 antibody (bs-9044R) Dilution:1ug/Test; Secondary Antibody(white blue line): Goat anti-rabbit IgG-FITC Dilution: 0.5ug/Test. Isotype control(orange line): Normal Rabbit IgG Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 五月天久久777| 久草在线手机视频 | 一本久道综合在线中文无码 | 国产亚洲视频网站 | 久久久久视 | 日本少妇人妻XXXXⅩ18 | 四虎欧美 | 成人一级片免费看 | www亚洲最大aⅴ成人天堂 | 91亚洲一区精品 | 免费看的黄色av网站 | 裸男网站gv | 免费无码中文A级毛片 | 国产精品一区二区精品 | 欧美一级日韩一级亚洲一级 | 国产成人精品午夜福利 | 国产日产免费高清欧美一区 | 日韩精品在线一区二区 | 午夜国产在线观看 | wwwxxx在线播放 | 日韩不卡中文字幕 | 男人插女人免费视频 | 波多野结衣视频在线 | 国产野精品久久久久久久不卡 | 欧洲成人18片 | 69一区二区 | 国产91一区二区在线观看 | 欧美人成精品网站播放 | 91在线网站 | 国精品产一区二区三区在线播放 | 国产精区| 热99RE久久精品这里都是精品免费 | 东北老女人高潮疯狂过瘾对白 | 欧美黄色一级片视频 | 久久久少妇高潮久久久久 | 精品国产乱码91久久久久久网站 | ww939766com永久免费 | 强行肉体进入hdxxxx办公室 | 在线观看av网 | 中文字幕第25页 | 激情三级|