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IGSF9 Rabbit pAb (bs-9199R)  
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產(chǎn)品編號 bs-9199R
英文名稱 IGSF9 Rabbit pAb
中文名稱 免疫球蛋白超家族成員9抗體
別    名 IGSF9A; Dasm1; Dendrite arborization and synapse maturation protein 1; IGSF9 immunoglobulin superfamily, member 9; Immunoglobulin superfamily member 9A; immunoglobulin superfamily, member 9; Ncaml; Nrt1; Protein turtle homolog A; TUTLA_HUMAN.  
研究領域 細胞生物  神經(jīng)生物學  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog)
產(chǎn)品應用 Flow-Cyt=1μg /Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 124 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IGSF9: 551-680/1179 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF9 (immunoglobulin superfamily, member 9), also known as Nrt1 or IGSF9A, is a 1,179 amino acid single-pass type I membrane protein expressed in a wide variety of fetal tissues at eight and fourteen weeks of gestation. Belonging to the immunoglobulin superfamily and the Turtle family, IGSF9 is thought to play a role in dendrite outgrowth and synapse maturation. IGSF9 contains two fibronectin type-III domains and five Ig-like (immunoglobulin-like) domains. IGSF9 interacts with MAGI-2 and Shank 1, both of which contain SH3 (Src-homology 3) domains. Protein-protein interactions are central events in cellular signal transduction and are often mediated by SH3 domains. IGSF9 is encoded by a gene located on human chromosome 1q23.2 and mouse chromosome 1 H3.

Function:
Functions in dendrite outgrowth and synapse maturation (By similarity).

Subunit:
Interacts with MAGI2 and SHANK1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the immunoglobulin superfamily. Turtle family.
Contains 2 fibronectin type-III domains.
Contains 5 Ig-like (immunoglobulin-like) domains.

SWISS:
Q9P2J2

Gene ID:
57549

Database links:

Entrez Gene: 57549 Human

Entrez Gene: 93842 Mouse

Entrez Gene: 304982 Rat

Omim: 609738 Human

SwissProt: Q9P2J2 Human

SwissProt: Q05BQ1 Mouse

SwissProt: P0C5H6 Rat

Unigene: 591472 Human



產(chǎn)品圖片
Blank control(blue): Hepg2 Cells(fixed with 2% paraformaldehyde (10 min)). Primary Antibody: Rabbit Anti-IGSF9/FITC Conjugated antibody (bs-9199R /FITC), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG/FITC(orange) ,used under the same conditions.
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