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CK15 Rabbit pAb (bs-4762R)  
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產品編號 bs-4762R
英文名稱 CK15 Rabbit pAb
中文名稱 細胞角蛋白15抗體
別    名 K1C15_HUMAN; Cytokeratin 15; CK 15; CK15; Cytokeratin15; K15; K1CO; Keratin 15; Keratin 15 basic; Keratin 15 beta; Keratin complex 1 acidic gene 15; Keratin type I cytoskeletal 15; Keratin15; KRT 15; KRTB; KRTL15; keratin-15, basic; Type I cytoskeletal 15.  
Specific References  (3)     |     bs-4762R has been referenced in 3 publications.
[IF=2.792] Yan, Wei. et al. Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats. BMC VET RES. 2022 Dec;18(1):1-18  IF, WB ;  Goat.  
[IF=1.92] Li et al. miR?339?5p negatively regulates loureirin A?induced hair follicle stem cell differentiation by targeting DLX5. (2018) Mol.Med.Rep. 18:1279-1286  ICC ;  Rat.  
[IF=1.329] Ziwei Luo. et al. miR‐203a‐3p promotes loureirin A‐induced hair follicle stem cells differentiation by targeting Smad1. Anat Rec. 2021 Mar;304(3):531-540  IF ;  Rat.  
研究領域 細胞生物  免疫學  信號轉導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 49 kDa
檢測分子量
細胞定位 細胞核 細胞漿 細胞外基質 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CK15: 351-456/456 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq, Jul 2008].

Subunit:
Heterotetramer of two type I and two type II keratins.

Tissue Specificity:
Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.

Similarity:
Belongs to the intermediate filament family.

SWISS:
P19012

Gene ID:
3866

Database links:

Entrez Gene: 3866 Human

Entrez Gene: 16665 Mouse

Entrez Gene: 287700 Rat

Omim: 148030 Human

SwissProt: P19012 Human

SwissProt: Q61414 Mouse

SwissProt: Q6IFV3 Rat

Unigene: 654570 Human

Unigene: 440010 Mouse

Unigene: 153568 Rat



產品圖片
Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti- CK15 (bs-4762R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 49 kD
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