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Defensin beta 2 Rabbit pAb (bs-4307R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-4307R
英文名稱 Defensin beta 2 Rabbit pAb
中文名稱 防御素β2抗體
別    名 beta Defensin 2; beta-defensin 2; mBD-2; Defensin, beta 2; Defb2; MGC129140; MGC129141; Skin-antimicrobial peptide 1; SAP1; BD-2; BD 2; BD2; beta 4 Defensin; DEF B2; DEF B4; DEFB 102; DEFB 2; DEFB-2; DEFB 4; DEFB102; DEFB2; DEFB4; Defensin 4 beta; Defensin beta 4; HBD-2; HBD 2; HBD2; SAP 1; SAP1; Skin antimicrobial peptide 1; DFB4A_HUMAN; DFB4A_RAT; DEFB4A.  
Specific References  (3)     |     bs-4307R has been referenced in 3 publications.
[IF=4.494] Nur Atalay. et al. Serum, saliva, and gingival tissue human β-defensin levels in relation to retinoic acid use. J PERIODONTOL. 2022 Nov;:  IHC ;  Human.  
[IF=2.38] Al‐Samadi, Ahmed, et al. "Increased beta 2 defensin in recurrent aphthous ulcer." Oral Diseases (2014).  IHC-P ;  Human.  
[IF=0] Shi et al. Overexpression of human β-defensin 2 promotes growth and invasion during esophageal carcinogenesis. (2014) Oncotarget. 5:11333-44  IHC ;  Rat.  
研究領域 細胞生物  發育生物學  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 4 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human beta 2 Defensin: 24-64/64 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways

Function:
Has antibacterial activity.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in the skin and respiratory tract.

Similarity:
Belongs to the beta-defensin family. LAP/TAP subfamily.

SWISS:
O15263

Gene ID:
1673

Database links:

Entrez Gene: 100289462 Human

Entrez Gene: 1673 Human

Omim: 602215 Human

SwissProt: O15263 Human

Unigene: 105924 Human

Unigene: 721744 Human



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