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TMEM176B Rabbit pAb (bs-11876R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-11876R
英文名稱 TMEM176B Rabbit pAb
中文名稱 跨膜蛋白TMEM176B抗體
別    名 LR 8; LR8; TMEM176B; Transmembrane protein 176B; T176B_HUMAN.  
研究領(lǐng)域 細胞生物  神經(jīng)生物學(xué)  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human)
產(chǎn)品應(yīng)用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 29 kDa
檢測分子量
細胞定位 細胞核 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LR8/TMEM176B: 25-150/270 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Chromosome 7 is about 158 milllion bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The LR8 gene product has been provisionally designated LR8 pending further characterization.

Function:
LR8 may be involved in the control of dendritic cell maturation and thus may play a role in the induction or maintenance of allograft tolerance. It's function is unknown.

Subcellular Location:
Nuclear membrane; Multi pass membrane protein.

Tissue Specificity:
Expressed in lung and dermal fibroblasts.

Similarity:
Belongs to the TMEM176 family.

SWISS:
Q3YBM2

Gene ID:
28959

Database links:

Entrez Gene: 28959 Human

Omim: 610385 Human

SwissProt: Q3YBM2 Human



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