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CEP104 Rabbit pAb (bs-12005R)  
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產(chǎn)品編號 bs-12005R
英文名稱 CEP104 Rabbit pAb
中文名稱 甘氨酸結(jié)合蛋白抗體
別    名 CE104_HUMAN; Centrosomal protein of 104 kDa; Cep104; GlyBP; Glycine Binding Protein; glycine-, glutamate-and thienylcyclohexylpiperidine-binding protein; KIAA0562; LOC246295.  
研究領(lǐng)域 腫瘤  細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Mouse (predicted: Rat,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45/104 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CEP104/KIAA0562: 451-550/925 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The KIAA0562 gene product has been provisionally designated KIAA0562 pending further characterization.

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole.

Similarity:
Contains 2 HEAT repeats.

SWISS:
O60308

Gene ID:
9731

Database links:

Entrez Gene: 9731 Human

Entrez Gene: 230967 Mouse

SwissProt: O60308 Human

SwissProt: Q80V31 Mouse

Unigene: 133089 Human

Unigene: 509017 Human

Unigene: 297905 Mouse



產(chǎn)品圖片
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti- CEP104 (bs-12005R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45’104 kD Observed band size: 104 kD
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