97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
久久综合久久自在自线精品自,亚洲欧美最新,国内精品久久久久久久小说
首頁 > 產品中心 > 一抗 > 產品信息
GPR17 Rabbit pAb (bs-12022R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-12022R
英文名稱 GPR17 Rabbit pAb
中文名稱 G蛋白偶聯受體17抗體
別    名 DKFZp686M18273; G protein coupled receptor 17; G-protein coupled receptor 17; GPR 17; Gpr17; GPCR17; GPR17_HUMAN; P2Y like receptor; P2Y-like receptor; Probable P2Y purinoceptor GPR 17; Probable P2Y purinoceptor GPR17; R12; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor.  
研究領域 神經生物學  信號轉導  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR17: 1-100/367 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 G protein-coupled receptor 17, GPR17, also known as uracil nucleotide/cysteinyl leukotriene receptor or P2Y-like receptor (P2YL), is a 367 amino acid member of the G-protein coupled receptor 1 family of proteins. While GPR17 is expressed in kidney, heart and umbilical vein endothelial cells, it is expressed in the highest levels in the brain. Upon brain injury, the extracellular concentrations of nucleotides and cysteinyl leukotrienes (CysLTs), two families of endogenous signaling molecules, increase significantly at the site of damage. In some neurons, GPR17, a membrane receptor for uracil nucleotide and CysLTs, is upregulated as well, infiltrating the lesioned area. GPR17 is thought to play a role in mediating neuronal death, remodeling brain circuitries by microglia and initiating remyelination in damaged neurons. Two named isoforms of GPR17 exist as a result of alternative splicing events.

Function:
Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q13304

Gene ID:
2840

Database links:

Entrez Gene: 2840 Human

Entrez Gene: 574402 Mouse

Entrez Gene: 767613 Rat

Omim: 603071 Human

SwissProt: Q13304 Human

SwissProt: Q6NS65 Mouse

SwissProt: Q09QM4 Rat

Unigene: 46453 Human

Unigene: 688940 Human

Unigene: 391108 Mouse

Unigene: 212749 Rat



產品圖片
Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Primary: Anti-GPR17 (bs-12022R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kDa Observed band size: 50 kDa
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 91动漫网站 | 一级色毛片 | 久久精品无码观看TV | 完全着衣の爆乳お姉さんが | eeuss影院www免费播放 | 人人妻人人澡人人爽超污 | 一二三区不卡 | 色悠久久久久综合网香蕉 | 日本人亚洲人jjzzjjz | 毛片无码一区二区三区a片视频 | 永久免费黄色 | 久久综合久久综合九色 | 一级免费看片 | 蜜桃臀AV高潮无码 | 在线视屏| 国产东北肥熟老胖女 | 久久99精品久久久久久久久久 | 男人扒开女人内裤强吻桶进去 | 免费无码国产V片在线观看 久久久激情网 | 91日韩精品一区二区三区 | 日韩精美视频 | 国产精品人妻无码久久久郑州天气网 | 天堂色网| 国产性AV在线 | 又黄又湿又免费视频 | 人人射人人草 | 永久免费看啪啪网址入口 | 狼人无码中文在线观看 | 欧美日韩在线第一页 | 91爱在线观看 | 国产一区影院 | 无码人妻丰满熟妇区a?v | 精品久久中文字幕97 | 一区二区三区视频免费视频观看网站 | 日本老熟妇maturebbw | 亚洲欧美天堂在线 | 国产精品久久久久无码av | 婷婷色一区 | 国产特级黄色片 | 国产午夜精华液 | 伊人中文字幕在线观看 |