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GABRR1 Rabbit pAb (bs-12084R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-12084R
英文名稱 GABRR1 Rabbit pAb
中文名稱 G氨基丁酸A型受體rho1/GABAA Rρ1抗體
別    名 bA135P14.1(gamma-aminobutyric acid(GABA) receptor rho 1); GABA(A) receptor subunit rho-1; gamma aminobutyric acid receptor rho 1; gamma-aminobutyric acid(GABA) A receptor rho-1; gamma-aminobutyric acid(GABA) receptor rho 1; gamma-aminobutyric acid receptor subunit rho-1; MGC163216; GBRR1_HUMAN.  
Specific References  (1)     |     bs-12084R has been referenced in 1 publications.
[IF=2.47] Kosonsiriluk, Sunantha, et al. "Enhanced GABAergic inhibition in the premammillary nucleus of photorefractory turkey hens via GABA A receptor upregulation." General and Comparative Endocrinology (2016).  IHC-P ;  
研究領域 神經(jīng)生物學  通道蛋白  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat (predicted: Rabbit,Pig,Cow,Dog)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABRR1: 201-300/479 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Function:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand gated chloride channels. GABRR1 is a member of the rho subunit family

Subunit:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multipass membrane protein. Cell membrane; Multipass membrane protein.

Tissue Specificity:
Highly expressed in the retina and in a lesser extent in brain, lung and thymus.

Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily.

SWISS:
P24046

Gene ID:
2569

Database links:

Entrez Gene: 2569 Human

Omim: 137161 Human

SwissProt: P24046 Human

Unigene: 99927 Human



產(chǎn)品圖片
Sample: Eye (Mouse) Lysate at 40 ug Heart (Mouse) Lysate at 40 ug HepG2 (Human) Lysate at 30 ug Primary: Anti-GABRR1 (bs-12084R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD
25 ug total protein per lane of various lysates (see on figure) probed with GABRR1 polyclonal antibody, unconjugated (bs-12084R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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