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P2RX6 Rabbit pAb (bs-12110R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-12110R
英文名稱 P2RX6 Rabbit pAb
中文名稱 三磷酸腺苷受體P2X6抗體
別    名 ATP receptor; P2RX6; P2RX6_HUMAN; P2RXL1; P2X purinoceptor 6; P2X6; P2XM; Purinergic receptor; Purinergic receptor P2X like 1; Purinergic receptor P2X-like 1; Skeletal muscle expressed P2X.  
研究領域 腫瘤  神經生物學  信號轉導  細胞凋亡  通道蛋白  細胞膜受體  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 49 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human P2RX6: 55-160/441 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.

Function:
Receptor for ATP that acts as a ligand-gated ion channel.

Subunit:
Functional P2XRs are organized as homomeric and heteromeric trimers

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed predominantly in skeletal muscle.

Similarity:
Belongs to the P2X receptor family.

SWISS:
O15547

Gene ID:
9127

Database links:

Entrez Gene: 9127 Human

Entrez Gene: 18440 Mouse

Entrez Gene: 25041 Rat

Omim: 608077 Human

SwissProt: O15547 Human

SwissProt: O54803 Mouse

SwissProt: P51579 Rat

Unigene: 113275 Human

Unigene: 8032 Mouse

Unigene: 10258 Rat



產品圖片
Sample: Uterus (Mouse) Lysate at 40 ug Primary: Anti-P2RX6 (bs-12110R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 49 kD
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