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KCNF1 Rabbit pAb (bs-12173R)  
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產品編號 bs-12173R
英文名稱 KCNF1 Rabbit pAb
中文名稱 電壓門控性鉀通道蛋白亞基kv5.1抗體
別    名 IK 8; IK8; KCNF 1; KCNF; Kcnf1; KCNF1_HUMAN; kH 1; kH1; KV5.1; Potassium voltage-gated channel subfamily F member 1; MGC33316; Potassium channel KH1; Potassium channel Kv5.1; Potassium voltage gated channel subfamily F member 1; Potassium voltage-gated channel subfamily F member 1; Voltage gated potassium channel subunit Kv5.1; Voltage-gated potassium channel subunit Kv5.1.  
Specific References  (1)     |     bs-12173R has been referenced in 1 publications.
[IF=4.43] Slaats et al. Screen-based identification and validation of four new ion channels as regulators of renal ciliogenesis. (2015) J.Cell.Sc. 128:4550-9  IF,WB ;  Mouse.  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,GuineaPig,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNF1: 161-260/494 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.

Function:
Putative voltage-gated potassium channel.

Subunit:
Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1.

Subcellular Location:
Membrane.

Tissue Specificity:
Detected in heart, brain, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the potassium channel family.
F (TC 1.A.1.2) subfamily. Kv5.1/KCNF1 sub-subfamily.

SWISS:
Q9H3M0

Gene ID:
3754

Database links:

Entrez Gene: 3754 Human

Entrez Gene: 382571 Mouse

Omim: 603787 Human

SwissProt: Q9H3M0 Human

SwissProt: Q7TSH7 Mouse

Unigene: 23735 Human

Unigene: 40173 Mouse



產品圖片
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti- KCNF1 (bs-12173R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD
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