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KCNG1 Rabbit pAb (bs-12174R)  
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產品編號 bs-12174R
英文名稱 KCNG1 Rabbit pAb
中文名稱 電壓門控性鉀通道蛋白亞基kv6.1抗體
別    名 K13; KCNG; kH2; KV6.1; Potassium voltage gated channel subfamily G; Potassium voltage gated channel subfamily G member 1; Voltage gated potassium channel subunit Kv6.1; KCNG1_HUMAN.  
研究領域 細胞生物  神經生物學  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,GuineaPig,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNG1: 401-500/513 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008].

Function:
KCNG1 is a member of the potassium channel, voltage-gated, subfamily G. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene is abundantly expressed in skeletal muscle. Alternative splicing results in at least two transcript variants encoding distinct isoforms.

Subunit:
Heterotetramer of potassium channel proteins (By similarity).

Subcellular Location:
Membrane; multi-pass membrane protein

Tissue Specificity:
Detected in brain and placenta, and at much lower levels in kidney and pancreas.

Similarity:
Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.1/KCNG1 sub-subfamily.

SWISS:
Q9UIX4

Gene ID:
3755

Database links:

Entrez Gene: 3755 Human

Entrez Gene: 241794 Mouse

Entrez Gene: 296395 Rat

Omim: 603788 Human

SwissProt: Q9UIX4 Human

SwissProt: A2BDX4 Mouse

Unigene: 118695 Human

Unigene: 91149 Rat



產品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KCNG1) Polyclonal Antibody, Unconjugated (bs-12174R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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