97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
瑟瑟视频在线观看,色多多成人福利视频,69热国产视频
首頁 > 產品中心 > 一抗 > 產品信息
SNX5 Rabbit pAb (bs-12248R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-12248R
英文名稱 SNX5 Rabbit pAb
中文名稱 分選連接蛋白5抗體
別    名 0910001N05Rik; 1810032P22Rik; AU019504; D2Ertd52e; FLJ10931; OTTHUMP00000030340; OTTHUMP00000062927; OTTMUSP00000003367; OTTMUSP00000003368; RP11-504H3.2; RP23-35E16.2; snoRNA MBI-43; SNX 5; SNX5; SNX5_HUMAN; Sorting nexin 5; Sorting nexin-5.  
研究領域 細胞生物  信號轉導  生長因子和激素  轉錄調節因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 47 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human SNX5: 2-75/404 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

Function:
May be involved in several stages of intracellular trafficking. Plays a role in macropinocytosis. Plays a role in the internalization of EGFR after EGF stimulation.

Subunit:
Interacts with SNX1; this promotes location at the endosome membrane.

Subcellular Location:
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cell projection, phagocytic cup. Cell projection, ruffle. Note=Recruited to the plasma membrane after EGF stimulation, which leads to increased levels of phosphatidylinositol 3,4-bisphosphate (PdtIns(3,4)P2). Detected on macropinosomes. Targeted to membrane ruffles in response to EGFR stimulation.

Similarity:
Belongs to the sorting nexin family.
Contains 1 BAR domain.
Contains 1 PX (phox homology) domain.

SWISS:
Q9Y5X3

Gene ID:
27131

Database links:

Entrez Gene: 514423 Cow

Entrez Gene: 27131 Human

Entrez Gene: 69178 Mouse

Entrez Gene: 296199 Rat

Omim: 605937 Human

SwissProt: Q3ZBM5 Cow

SwissProt: Q9Y5X3 Human

SwissProt: Q9D8U8 Mouse

SwissProt: B1H267 Rat



版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日韩精品美腿丝袜 | 久久久91精品国产一区二区精品 | 在线观看色网 | 国产美女久久 | 久久亚洲中文字幕伊人久久大 | 强插女教师AV在线 | 久久久精品一区二区三区 | 欧美性猛交久久久乱大交小说 | 国产理论一区二区三区 | 被黑人伦流澡到高潮hn小说 | 中国视频一区二区 | 99热色| 亚洲日韩av片在线观看 | 国产精品高潮呻吟av久久动漫 | hd法国xxxxhdvideos | 中文WWW新版资源在线 | 中文字幕亚洲精品无码 | 无码人妻一区二区三区免费N鬼沢 | 污污汅18禁在线无遮挡免费观看 | 99久久人人爽亚洲精品美女 | 欧美黑人又粗又大久久久 | 97精品一区二区三区 | 亚洲毛片AV日韩AV无码 | 亚洲日本成本人观看 | 在线精品亚洲一区二区动态图 | 色综合久久综合网 | 黄色a在线 | 国产精品久久久亚洲女人 | 精品在线观看一区二区三区 | 日本不卡免费高清视频在线 | 国产精品日韩欧美一区二区 | 国产香蕉一区二区三区 | 四虎亚洲精品私库AV在线 | 一区二区福利 | 久久人人爽人人爽人人片DVD | 久久综合香蕉国产蜜臀av | 狠狠综合久久久久综合网小蛇 | 脱了老师内裤猛烈进入在线观看 | 欧美黑人粗暴多交高潮水最多 | 久草视频免费观 | 欧美视频二区 |