97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
91素人在线,亚洲成年女人av毛片性性教育,最新日韩av在线
首頁 > 產品中心 > 一抗 > 產品信息
phospho-DAP Kinase 2 (Ser318) Rabbit pAb (bs-12980R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-12980R
英文名稱 phospho-DAP Kinase 2 (Ser318) Rabbit pAb
中文名稱 磷酸化凋亡相關蛋白激酶2抗體
別    名 DAP Kinase 2(phospho S318); p-DAP Kinase 2(phospho S318); Death associated protein kinase 2; DAK 2; DAK2; DAP kinase related protein 1; DAPK 2; DAPK2; Death associated protein kinase 2; DRP 1; DRP1; DRP-1; MGC119312; DAP kinase 2; DAP kinase related protein 1; DAP kinase related protein 1 beta isoform; DAP-kinase-related protein 1; DAPK 2; DAPK2; DAPK2_HUMAN; Death associated protein kinase 2; Death-associated protein kinase 2; DRP 1; DRP-1; DRP1; MGC119312.  
產品類型 磷酸化抗體 
研究領域 細胞生物  信號轉導  細胞凋亡  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,GuineaPig,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human DAP Kinase 2 around the phosphorylation site of Ser318: KL(p-S)FS 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Protein kinase termed (DAPK2) dependant on calcium/calmodulin (Ca2+/CaM) contains an N-terminal protein kinase domain followed by a conserved CaM-binding domain with significant homologies to those of DAP kinase, a protein kinase involved in apoptosis. Overexpression of DAPK2 significantly induced the morphological changes characteristic of apoptosis. Results indicate that DAPK2 is an additional member of DAP kinase family involved in apoptotic signaling.

Function:
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Required for normal brain development. Facilitates developmentally-regulated apoptosis during neural tube development. Required for a normal rate of cytochrome c release and caspase activation during apoptosis. Also required for mitochondrial fission during mitosis. May be involved in vesicle transport. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.

Subunit:
Homodimer in its autoinhibited state. Active as monomer. Isoform 2 but not isoform 1 can interact with ATF4.

Subcellular Location:
Cytoplasm. Cytoplasmic vesicle, autophagosome lumen.

Tissue Specificity:
Ubiquitously expressed with highest levels found in skeletal muscles, heart, kidney and brain. Isoform 1 is brain-specific. Isoform 2 and isoform 3 are predominantly expressed in testis and skeletal muscles respectively. Isoform 4 is weakly expressed in brain, heart and kidney. Isoform 5 is dominantly expressed in liver, heart and kidney. Isoform 6 is expressed in neurons.

Post-translational modifications:
Autophosphorylation at Ser-318 inhibits its catalytic activity. Dephosphorylated at Ser-318 in response to activated Fas and TNF-alpha receptors.

Similarity:
Belongs to the protein kinase superfamily.
CAMK Ser/Thr protein kinase family.
DAP kinase subfamily.
Contains 1 protein kinase domain.

SWISS:
Q9UIK4

Gene ID:
23604

Database links:

Entrez Gene: 23604 Human

Entrez Gene: 13143 Mouse

Entrez Gene: 300799 Rat

Omim: 604727 Human

SwissProt: Q9UIK4 Human

SwissProt: Q8VDF3 Mouse

Unigene: 237886 Human

Unigene: 304472 Mouse

Unigene: 335252 Mouse

Unigene: 98325 Rat



版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产乱插 | 欧美日韩一区二区精品 | 精品国产片 | 人人爽人人爽人人片A免费 国产国语农村妇女偷人视频 | 国产九色在线观看 | 国产大陆亚洲精品国产 | 亚洲国产成人精品无码区在线网站 | 亚洲人成色777777精品音频 | 千百橹av入口在线观看 | 欧美激情精品久久 | 国产精品自产拍在线观看55 | 久草在线免费在线观看 | 国产亚洲欧美日韩精品 | 好男人中文资源在线观看 | 一级免费看片 | 日韩美女爱爱 | 超碰中文字幕在线 | 亚洲国产成在人网站天堂 | 国产精品成人免费精品自在线观看 | 最新永久无码AV网址亚洲 | 国产午夜福利视频在线观看 | 久久99精品无码一区二区三区 | 亚洲高清成人 | 好吊操视频| 九色蝌蚪av新入口 | 在线中文字幕有码中文 | 国产精品久久久久久久婷婷 | 在线观看国产一区二区三区 | 国产亚洲专区 | 国产小视频免费观看 | 西西人体444WWW大胆无码视频 | 人妻av资源先锋影音av资源 | 国产精品久久久久久久久久免费 | 男女久久久国产一区二区三区 | 在线观看欧美日韩国产 | 日韩黄色大片在线观看 | 国产中日韩久久久噜噜久久 | 孕妇奶水仑乱A级毛片免费看 | 欧美乱妇日本无乱码特黄大片 | 成年人在线免费观看视频网站 | 97香蕉久久超级碰碰高清版 |