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ZBTB7C Rabbit pAb (bs-13583R)  
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產品編號 bs-13583R
英文名稱 ZBTB7C Rabbit pAb
中文名稱 鋅指蛋白ZBTB7C抗體
別    名 APM 1; APM1; B230208J24Rik; FLJ37907; ZBTB36; Zinc finger and BTB domain containing 7C.  
Specific References  (1)     |     bs-13583R has been referenced in 1 publications.
[IF=3.375] Xuenuo Chen. et al. Zinc finger and BTB domain-containing 7C (ZBTB7C) expression as an independent prognostic factor for colorectal cancer and its relevant molecular mechanisms. Am J Transl Res. 2020; 12(8): 4141–4159  IHC ;  Human.  
研究領域 轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Chicken,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 69 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZBTB7C: 351-450/619 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Zinc finger and BTB domain-containing protein 7C (ZBTB7C), also designated affected by papillomavirus DNA integration in ME180 cells protein 1 (APM-1), contains 1 BTB (POZ) domain and 4 C2H2-type zinc fingers. ZBTB7C is detected in normal cervical keratinocytes and may be a potential tumor suppressor gene against human papillomavirus (HPV) mediated cervical carcinogenesis.

Function:
The function of Anti-ZBTB7C has not yet been determined.

Tissue Specificity:
Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines.

Similarity:
Contains 1 BTB (POZ) domain.
Contains 4 C2H2-type zinc fingers.

SWISS:
A1YPR0

Gene ID:
201501

Database links:

Entrez Gene: 201501 Human

Entrez Gene: 207259 Mouse

SwissProt: A1YPR0 Human

SwissProt: Q8VCZ7 Mouse

Unigene: 515388 Human



產品圖片
Sample: A549 (human)Cell Lysate at 40 ug Primary: Anti-ZBTB7C(bs-13583R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 69 kD Observed band size: 63 kD
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