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SOX30 Rabbit pAb (bs-13611R)  
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50ul/1180.00元
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產品編號 bs-13611R
英文名稱 SOX30 Rabbit pAb
中文名稱 轉錄因子SOX30抗體
別    名 Sex determining region Y box 30; Sox30 protein type II; SRY box 30; SRY related HMG box 30; Transcription factor SOX 30; SOX30_HUMAN.  
研究領域 細胞生物  發育生物學  干細胞  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 82 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SOX30: 351-450/753 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Sox-30 encodes a member of the Sox (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Sox-30 is expressed in testis and may act as a transcriptional regulator after forming a protein complex with other proteins. Sox-30 may be involved in the differentiation of developing male germ cells. Two transcript variants encoding distinct isoforms have been identified for the human Sox-30 gene. Sox family transcription factors influence cell differentiation, development and sex determination. Sox-30 contains a unique DNA binding domain, known as the high mobility group (HMG) box, that is related to that of the testis determining gene, SRY. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. Several Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development.

Function:
SOX30 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein may be involved in the differentiation of developing male germ cells.

Subcellular Location:
Nuclear

Tissue Specificity:
Expressed in testis.

Similarity:
Contains 1 HMG box DNA-binding domain.

SWISS:
O94993

Gene ID:
11063

Database links:

Entrez Gene: 11063 Human

Entrez Gene: 214105 Mouse

Omim: 606698 Human

SwissProt: O94993 Human

SwissProt: Q8CGW4 Mouse

Unigene: 744348 Human



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