97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲精品久久无码AV片俺去也,久久视频一区二区,尤物精品视频
首頁 > 產品中心 > 一抗 > 產品信息
GRB7 Rabbit pAb (bs-13642R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-13642R
英文名稱 GRB7 Rabbit pAb
中文名稱 生長因子受體結合蛋白7抗體
別    名 B47; Epidermal growth factor receptor GRB 7; Epidermal growth factor receptor GRB-7; GRB7 adapter protein; GRB7; GRB7_HUMAN; Growth factor receptor bound protein 7; Growth factor receptor-bound protein 7; OTTHUMP00000164349; OTTHUMP00000164350; OTTHUMP00000164351; OTTHUMP00000164352.  
研究領域 腫瘤  細胞生物  信號轉導  激酶和磷酸酶  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GRB7: 231-330/532 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Many growth factors function by binding receptors with intrinsic tyrosine kinase activity (1,2). Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and the phosphotyrosine-containing receptor sequences (3,4). GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N-terminus (5,6). GRB7 maps to the region on mouse chromosome 11 containing the Neu gene (6). This region of mouse chromosome 11 is syntenic to an area of human chromosome 17q that is frequently amplified in breast cancer (6,7). Moreover, GRB7 is amplified and over-expressed in breast cancer and is found in a complex with Neu gp185 (6).

Function:
Interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. Also binds to ERBB2.

Post-translational modifications:
Phosphorylated on tyrosine residues.

Similarity:
Belongs to the GRB7/10/14 family.
Contains 1 PH domain.
Contains 1 Ras-associating domain.
Contains 1 SH2 domain.

SWISS:
Q14451

Gene ID:
2886

Database links:

Entrez Gene: 2886 Human

Entrez Gene: 14786 Mouse

Entrez Gene: 84427 Rat

Omim: 601522 Human

SwissProt: Q14451 Human

SwissProt: Q03160 Mouse

SwissProt: Q9QZC5 Rat

Unigene: 86859 Human



版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 天天碰日日操 | 无码一区二区三区免费 | 精品久久AⅤ人妻中文字幕 国产高清无码黄片亚洲大尺度视频 | 一区二区三区四区乱码 | 爆乳放荡的女教师bd | 成人一区在线观看 | 在线观看av黄色 | 国产成人精品国内自产拍免费看 | 91视频一区 | 国产极品美女高潮抽搐免费网站 | 91亚洲精品第一 | 啊v视频在线 | 日韩欧精品无码三级片 | 国产一区二区成人久久免费影院 | 尤物爆乳av导航 | 婷婷色怡春院 | 国产香蕉一区二区在线网站 | 性欧美另类黑人巨大HD | 狠狠操操 | 夜色资源站ye321mp4 | 久久国产中文字幕 | 天天综合网久久综合网 | 欧美性视频在线看 | www.av小次郎| 国产一级视频免费看 | 少妇撒尿一区二区在线视频 | 女人爽到高潮免费视频大全 | 极品少妇XXXX | 伊人福利| 亚洲7天堂人人爽人人爽 | 又黄又湿又免费视频 | 亚洲精品AV一区午夜福利 | 免费黄色大片 | 色八a级在线观看 | 囯产精品久久久久久久久久妞妞 | 亚韩精品 | 亚洲精品美女视频在线观看 | 亚洲成人高清av | 91精品在线免费视频 | 国产高清一级毛片在线不卡 | 性色av蜜臀av牛牛影院 |