| 產(chǎn)品編號 | bs-17163R |
| 英文名稱 | TPCN1 Rabbit pAb |
| 中文名稱 | 電壓依賴性鈣通道蛋白抗體 |
| 別 名 | FLJ20612; KIAA1169; TPC1; TPC1_HUMAN; TPCN 1; TPCN1; Two pore calcium channel protein 1; Two pore channel 1; Two pore segment channel 1; Voltage dependent calcium channel protein TPC1; Voltage-dependent calcium channel protein TPC1. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 通道蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 94 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TPCN1: 701-800/816 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]).[supplied by OMIM, Mar 2008] Function: Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal and endosomal membrane. Subcellular Location: Lysosome membrane. Endosome membrane. Tissue Specificity: Highest expression found in the heart and kidney, and lowest expression found in the spleen. Similarity: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily. SWISS: Q9ULQ1 Gene ID: 53373 Database links: Entrez Gene: 53373 Human Entrez Gene: 252972 Mouse Entrez Gene: 567534 Zebrafish Omim: 609666 Human SwissProt: Q9ULQ1 Human SwissProt: Q9EQJ0 Mouse Unigene: 524763 Human Unigene: 114054 Mouse Unigene: 24484 Rat |
