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MPP6/MPHOSPH6 Rabbit pAb (bs-17687R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-17687R
英文名稱 MPP6/MPHOSPH6 Rabbit pAb
中文名稱 M-期磷蛋白6抗體
別    名 M phase phosphoprotein 6; M phase phosphoprotein 6 variant; M-phase phosphoprotein 6; MPH6_HUMAN; MPHOSH6; MPHOSPH 6; Mphosph6; MPP-6; MPP; MPP6.  
研究領域 細胞生物  細胞粘附分子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Rat (predicted: Human,Mouse,Rabbit,Sheep,Cow)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 19 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MPP6: 1-80/160 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 MPHOSPH6 (M-Phase Phosphoprotein 6) is a Protein Coding gene. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA binding.

Function:
RNA-binding protein that associates with the RNA exosome complex. Involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and play a role in recruiting the RNA exosome complex to pre-rRNA; this function may include C1D.

Subunit:
Associates with the RNA exosome complex, probably mediated by EXOSC10. Interacts with ARHGAP18, EXOSC10 and SKIV2L2.

Subcellular Location:
Nucleus > nucleolus. Cytoplasm. Cytoplasmic in M phase.

Post-translational modifications:
Phosphorylated in M (mitotic) phase.

Similarity:
Belongs to the MPP6 family.

SWISS:
Q99547

Gene ID:
10200

Database links:

Entrez Gene: 10200 Human

Entrez Gene: 68533 Mouse

Omim: 605500 Human

SwissProt: Q99547 Human

SwissProt: Q9D1Q1 Mouse

Unigene: 344400 Human

Unigene: 181836 Mouse



產品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MMP6/MPHOSPH6) Polyclonal Antibody, Unconjugated (bs-17687R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat urinary bladder); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MMP6/MPHOSPH6) Polyclonal Antibody, Unconjugated (bs-17687R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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