97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
影音先锋色AV男人资源网,91成人网在线播放,宅男99
首頁 > 產品中心 > 一抗 > 產品信息
LIM kinase 2b Rabbit pAb (bs-18270R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-18270R
英文名稱 LIM kinase 2b Rabbit pAb
中文名稱 LIM結構域激酶2抗體
別    名 LIM containing protein kinase 2b; LIM domain kinase 2; LIM domain kinase 2b; LIM kinase 2b; LIM motif containing protein kinase 2b; LIMK 2b; LIMK-2; Limk2; LIMK2 b; LIMK2_HUMAN; LIMK2b.  
研究領域 細胞生物  信號轉導  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 68 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LIM kinase 2b: 1-16/617 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.

Subcellular Location:
Cytoplasm. Nucleus. Isoform LIMK2a is distributed in the cytoplasm and the nucleus and Cytoplasm. Nucleus. Isoform LIMK2b occurs mainly in the cytoplasm and is scarcely translocated to the nucleus.

Tissue Specificity:
Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed.

Post-translational modifications:
Phosphorylated on serine and/or threonine residues by ROCK1.

Similarity:
Belongs to the protein kinase superfamily.
TKL Ser/Thr protein kinase family.
Contains 2 LIM zinc-binding domains.
Contains 1 PDZ (DHR) domain. Contains 1 protein kinase domain.

SWISS:
P53671

Gene ID:
3985

Database links:

Entrez Gene: 3985 Human

Omim: 601988 Human

SwissProt: P53671 Human

Unigene: 474596 Human



版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 成人国产精品色哟哟 | 真人插b免费视频播放 | 免费在线观看亚洲视频 | 日韩AV无码中文字幕 | 国产欧美日本一区二区三区 | 最近免费中文字幕在线mv视频8 | www.91在线观看 | 精品一区二区三区视频日产 | 国产一级一片免费播放 | 高清一区二区中文字幕 | 色影天堂 | 国产女同一区二区在线 | 国产精品亚洲专区无码影院 | 中文字幕第25页 | 欧美一级www片免费观看 | 免费一级好看的国产 | 欧美性猛交╳XXX富婆 | 日韩一级色片 | 香蕉久久综合 | 国产又大又粗又爽的毛片 | 国产黑色丝袜在线视频 | 免费在线观看一区二区 | 丁香五月色情婷婷在线观看 | 天天干夜夜爽 | 少妇人妻偷人精品无码视频 | 中文人妻无码一区二区三区 | 午夜精品成人一区二区 | 色视频www在线播放国产人成 | 国产偷国产偷亚洲高清日韩 | 国产一级片网站 | 亚洲自偷自偷图片 | 青青爽在线视频 | 99超碰在线人人 | 亚洲AV无码精品色午夜蜜芽 | 手机在线色 | 亚洲国产一级毛片 | 亚洲麻豆精品 | 人人草人人做人人爱 | 一区福利在线 | 国产无套露脸在线观看 | 一区二区不卡在线播放 |