97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
毛片免费在线视频,国产一级小视频,亚洲特黄a级毛片在线播放
首頁 > 產品中心 > 一抗 > 產品信息
phospho-NFAT2 (Ser233) Rabbit pAb (bs-19785R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-19785R
英文名稱 phospho-NFAT2 (Ser233) Rabbit pAb
中文名稱 磷酸化活化T細胞核因子1蛋白抗體
別    名 NFAT2(phospho S233); p-NFAT2(phospho S233); p-NFAT2(Ser235 mouse); NFAT2; MGC138448; NF ATc; NF ATc1; NFAT 2; NFATc1; NFAT transcription complex cytosolic component; NFATC 1; NFATc; NFATc1; Nuclear factor of activated T cells cytoplasmic 1; Nuclear factor of activated T cells cytoplasmic calcineurin dependent 1; Nuclear factor of activated T cells cytosolic component 1; NFAC1_HUMAN.  
Specific References  (1)     |     bs-19785R has been referenced in 1 publications.
[IF=8.109] Ling Wu. et al. Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation. Cell Rep. 2020 Oct;33:108327  IF,IHC ;  Human.  
產品類型 磷酸化抗體 
研究領域 細胞生物  神經生物學  細胞凋亡  轉錄調節因子  t-淋巴細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Rat (predicted: Mouse,Pig,Sheep,Cow)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 101 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human NFAT2 around the phosphorylation site of Ser233: LG(p-S)SP 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described. [provided by RefSeq, Jul 2008]

Function:
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.

Tissue Specificity:
Expressed in thymus, peripheral leukocytes as T-cells and spleen. Isoforms A are preferentially expressed in effector T-cells (thymus and peripheral leukocytes) whereas isoforms B and isoforms C are preferentially expressed in naive T-cells (spleen). Isoforms B are expressed in naive T-cells after first antigen exposure and isoforms A are expressed in effector T-cells after second antigen exposure.

Post-translational modifications:
Phosphorylated by NFATC-kinase; dephosphorylated by calcineurin.

Similarity:
Contains 1 RHD (Rel-like) domain.

SWISS:
O95644

Gene ID:
4772

Database links:

Entrez Gene: 4772 Human

Omim: 600489 Human

SwissProt: O95644 Human

Unigene: 534074 Human

Unigene: 701518 Human



產品圖片
Sample: K562(Human) Cell Lysate at 30 ug Primary: Anti-phospho-NFAT2 (Ser233) (Ser235 mouse)(bs-19785R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 101 kD Observed band size: 101 kD
Paraformaldehyde-fixed, paraffin embedded (Rat spleen); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (phospho-NFAT2 (Ser233) (Ser235 mouse)) Polyclonal Antibody, Unconjugated (bs-19785R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 欧美成人一区二区三区在线观看 | 天堂在线精品视频 | 天堂AV无码大芭蕉伊人AV孕妇 | 久久久一区二区三区 | 国产精品久久久久久久久吹潮 | 亚洲欧美在线成人 | 国产精品久久久久久久亚洲按摩 | 免费无码一区二区三区 | 国产特级毛片aaaaaaa高清 | 国产性AV在线 | 国产无遮挡色视频免费观看性色 | 伊人插插插 | 老少配videoshd乱配 | 人妻系列无码专区久久五月天 | 中文字幕视频在线 | 性做久久久久久免费观看软件 | 国产av无码专区亚洲avjulia | 日韩欧美有码 | 亚洲精品在线观看视频 | 国产精品久久免费视频在线 | 黄色免看 | 日本黄网免费一区二区精品 | 神马久久久久久久久久久 | 国内精品久久久久国产盗摄 | 久久精品久久精品久久精品 | 看av免费毛片手机播放 | 亚洲国产欧美在线人成最新 | 91免费高清观看 | 丰满妇女做A级毛片 | va久久久久精码专区 | 在教室伦流澡到高潮H强圩动漫 | 91精品国产乱码久久久软件 | 精品久久综合1区2区3区激情 | 亚洲精品国产福利 | 日产中文字幕在线观看 | 国产精品久久99精品毛片三a | 国产偷久久一级精品 | 午夜a级毛片免费观看 | 国产在线精品拍揄自揄免费 | 亚洲黄色一级毛片 | 国产香蕉一区二区在线网站 |