97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
91传媒免费网站,国产尤物av尤物在线观看臀,mmm·www看片免费观看
首頁 > 產品中心 > 一抗 > 產品信息
phospho-RhoGDI (Ser174) Rabbit pAb (bs-19875R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-19875R
英文名稱 phospho-RhoGDI (Ser174) Rabbit pAb
中文名稱 磷酸化腫瘤轉移抑制基因GDIA1抗體
別    名 RhoGDI(phospho S174); p-RhoGDI(phospho S174); ARHGDIA; fa96g11; GDIA 1; GDIA1; GDIR1_HUMAN; MGC117248; NPHS8; Rho GDI 1; Rho GDI alpha; Rho GDI; Rho GDP dissociation inhibitor(GDI) alpha; Rho GDP dissociation inhibitor 1; Rho GDP dissociation inhibitor alpha; Rho GDP-dissociation inhibitor 1; Rho-GDI alpha; RhoGDI 1; RhoGDI alpha; RHOGDI; RhoGDI1; wu:fa96g11; zgc:55554; zgc:77681.  
產品類型 磷酸化抗體 
研究領域 細胞生物  信號轉導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Cow)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 23 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human RhoGDI around the phosphorylation site of Ser174: RG(p-S)YS 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Function:
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.

Subunit:
Monomer. Interacts with FER. Interacts with PLXNB3 (By similarity). Forms a heterodimer with RAC1. Interacts with RHOA, the affinity is increased by three orders of magnitude when RHOA is prenylated. Interacts with PSMD10; the interaction increases ARHGDIA association with RHOA, leading to ARHGDIA-mediated inactivation of RHOA and ROCK and prolonged AKT activation. Interacts with RHOC and CDC42.

Subcellular Location:
Cytoplasm.

DISEASE:
The disease is caused by mutations affecting the gene represented in this entry.
Disease description:A form of nephrotic syndrome, a renal disease clinically characterized by progressive renal failure, severe proteinuria, hypoalbuminemia, hyperlipidemia and edema. Kidney biopsies show diffuse mesangial sclerosis, with small glomeruli, hypercellularity, increased extracellular matrix, and contracted/collapsed glomerular tufts surrounded by immature or abnormal podocytes.

Similarity:
Belongs to the Rho GDI family.

SWISS:
P52565

Gene ID:
396

Database links:

Entrez Gene: 396 Human

Entrez Gene: 192662 Mouse

Entrez Gene: 360678 Rat

Omim: 601925 Human

SwissProt: P52565 Human

SwissProt: Q99PT1 Mouse

SwissProt: Q5XI73 Rat

Unigene: 159161 Human

Unigene: 30016 Mouse

Unigene: 474783 Mouse

Unigene: 1801 Rat



產品圖片
Sample: Hela Cell (Human) Lysate at 40 ug HepG2 Cell (Human) Lysate at 40 ug Primary: Anti- phospho-RhoGDI (Ser174) (bs-19875R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 23 kD Observed band size: 23 kD
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲人成网站在小说 | 婷婷丁香色综合狠狠色 | 高潮一区二区 | 国外欧美一区另类中文字幕 | 国产欧美亚洲精品 | 91视频99 | av二区在线观看 | 91麻豆入口| 美日韩一级大片 | 欧美人与动性xxxxx交性 | 欧美片网站免费 | 亚洲综合无码日韩 | 我老公的家庭教师 | 成人天堂 | 久久久久久精品一区二区三区日本 | 日韩美女福利视频 | 亚洲人成自拍网站在线观看 | 男人日批 | 影院亚洲| 亚洲中文无码成人影院 | 成人手机在线视频 | 亚洲大乳av成人天堂精品 | 国产小视频a | 高潮毛片无遮挡免费高清 | 成人综合激情 | 欧美视频免费在线 | 欧洲免费无线码在线一区 | 91成人破解版| 狂野欧美激情性XXXX按摩 | 色视频在线免费 | 成人网在线观看视频 | 欧美日韩激情一区二区 | 日韩精品99 | 国产人妻高清国产拍精品 | yy111111少妇影院免费 | 综合视频在线 | 精品丝袜国产自在线拍高清 | 男人久久久 | 级R片内射在线视频播放 | 亚洲麻豆av肉丝网站一区二区 | 唐人街探案网剧免费观看 |