97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
成年人免费网站在线观看,夜夜艹图,国产在线一区二区综合免费视频
首頁 > 產品中心 > 一抗 > 產品信息
CATSPER Rabbit pAb (bs-23326R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-23326R
英文名稱 CATSPER Rabbit pAb
中文名稱 陽離子通道精子相關蛋白1抗體
別    名 ation channel sperm associated 1; Cation channel sperm associated protein 1; CATSPER 1; CATSPER; hCatSper; MGC33335; MGC33368; Sperm associated cation channel 1; Sperm ion channel; CTSR1_HUMAN; Cation channel sperm-associated protein 1; CatSper1; hCatSper.  
研究領域 細胞生物  發育生物學  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 90 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CATSPER: 551-650/780 <Extracellular>
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 CATSPER1 is a voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. It controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. It is activated by intracellular alkalinization.

Function:
Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH.

Subunit:
Heterotetramer; possibly composed of CATSPER1, CATSPER2, CATSPER3 and CATSPER4 (Potential). Component of the CatSper complex. Interacts with CATSPER3 and CATSPER4. Interacts with Ca(v)3.3/CACNA1I, leading to suppress T-type calcium channel activity.

Subcellular Location:
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specifically located in the principal piece of sperm tail.

Tissue Specificity:
Testis-specific.

DISEASE:
Defects in CATSPER1 are the cause of spermatogenic failure type 7 (SPGF7) [MIM:612997]. An infertility disorder characterized by non-motile sperm or sperm motility below the normal threshold, low sperm count, increased abnormally structured spermatozoa, and reduced semen volume.

Similarity:
Belongs to the cation channel sperm-associated (TC 1.A.1.19) family.

SWISS:
Q8NEC5

Gene ID:
117144

Database links:

Entrez Gene: 117144 Human

Entrez Gene: 225865 Mouse

SwissProt: Q8NEC5 Human

SwissProt: Q91ZR5 Mouse



產品圖片
Sample: Lane 1: Human MCF-7 cell lysates Lane 2: Human K562 cell lysates Primary: Anti-CATSPER (bs-23326R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kDa Observed band size: 95 kDa
Sample: U2OS(Human) Cell Lysate at 30 ug Primary: Anti- CATSPER (bs-23326R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kD Observed band size: 90 kD
Paraformaldehyde-fixed, paraffin embedded (rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (CATSPER) Polyclonal Antibody, Unconjugated (bs-23326R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human lung); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (CATSPER) Polyclonal Antibody, Unconjugated (bs-23326R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse lung); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (CATSPER) Polyclonal Antibody, Unconjugated (bs-23326R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲一区二区三区视频在线 | 97人人模人人爽人人少妇 | 狠狠综合久久久久综合网小蛇 | 日本少妇高潮叫床声 | 夜夜高潮夜夜爽夜夜爱爱一区 | 18禁勿入午夜网站入口 | 久草高清在线 | 美日韩一级 | 无码少妇一区二区三区 | 久久精品亚洲男人的天堂 | www.亚洲精品 | 天堂在线精品视频 | 夜夜澡人摸人人添人人看 | 麻豆成人免费视频 | 在线观看无码AV网站永久免费 | 亚洲综合色丁香婷婷六月图片 | 国产尺码和欧洲尺码表2022 | 亚洲国产精品久久久久 | 日本一级片免费 | 九色最新 | 色av色av色av| 林雅诗三级无删减在线观看 | 男男做爰猛烈高潮在线观看 | 亚洲国产精品久久亚洲精品大牛 | 无码专区天天躁天天躁在线 | a黄在线观看 | 无码国内精品人妻少妇蜜桃视频 | 2019天天干天天操 | 日日弄天天弄美女bbbb | 国精产品一区二区三区四区 | 唐人街探案网剧免费观看 | haodiaoniu视频只精品 | 亚洲一区二区三区国产精品 | 久久精品欧洲 | 国产精品久久久久久人妻精品 | 波多野结衣中文字幕免费观看 | 成人九区| 国产精品久久久久久久久久新婚 | 中文字幕国内自拍 | 亚洲日本va在线观看 | 91插插插插插插插 |