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human CD3/PerCP (bsm-30061M-PerCP)  
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產(chǎn)品編號 bsm-30061M-PerCP
英文名稱 human CD3/PerCP
中文名稱 PerCP標(biāo)記人CD3單克隆抗體
別    名 CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon (CD3 TCR complex); CD3e molecule, epsilon (CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE.  PerCP Anti-Human CD3;
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  干細(xì)胞  細(xì)胞表面分子  淋巴細(xì)胞  t-淋巴細(xì)胞  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 UCHT1
交叉反應(yīng)
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 20kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
免 疫 原 NULL 
亞    型 IgG1
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Function:
The CD3 complex mediates signal transduction.

Subunit:
The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 1 ITAM domain.

SWISS:
P07766

Gene ID:
916

Database links:

Entrez Gene: 916 Human

Omim: 186830 Human

SwissProt: P07766 Human

Unigene: 3003 Human



產(chǎn)品圖片
Flow cytometry staining of normal human peripheral blood cells with CD3/PerCP(bsm-30061M-PerCP)(Red histogram) or Mouse IgG1 Isotype Control PerCP (C03-11003)(Blue histogram). Total cells were used for analysis.
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