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FOXD2 Rabbit pAb (bs-21592R)  
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產品編號 bs-21592R
英文名稱 FOXD2 Rabbit pAb
中文名稱 叉頭蛋白D2抗體
別    名 Drosphilia Forkhead Homolog Like 17; FKHL 17; Forkhead box protein D2; Forkhead Related Activator 9; Forkhead-related protein FKHL17; Forkhead-related transcription factor 9; FOXD2; FOXD2_HUMAN; FREAC 9; FREAC-9.  
研究領域 腫瘤  神經生物學  轉錄調節因子  轉運蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse (predicted: Rat,Rabbit,Pig,Cow)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 49 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FOXD2: 71-170/495 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. FOXD1 (also designated Brain Factor 2 or BF-2) is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NF-AT and NFkB. Deficiency of FOXD1 results in multiorgan, systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation.

Function:
Probable transcription factor involved in embryogenesis and somatogenesis.

Subcellular Location:
Nucleus.

Tissue Specificity:
Kidney specific.

Similarity:
Contains 1 fork-head DNA-binding domain.

SWISS:
O60548

Gene ID:
2306

Database links:
Entrez Gene: 2306 Human

Entrez Gene: 17301 Mouse

Omim: 602211 Human

SwissProt: O60548 Human

SwissProt: O35392 Mouse

Unigene: 166188 Human

Unigene: 7997 Mouse



產品圖片
Sample: Jurkat (Human) Cell Lysate at 30 ug Primary: Anti-FOXD2 (bs-21592R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 49 kD
Sample: Large intestine (Mouse) Lysate at 40 ug Primary: Anti- FOXD2 (bs-21592R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 49 kD
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