97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲男人网站,JAVAPARSERHD高潮,性中国hd
首頁 > 產品中心 > 一抗 > 產品信息
Phospho-TFEB(Ser142) Rabbit pAb (bs-22337R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-22337R
英文名稱 Phospho-TFEB(Ser142) Rabbit pAb
中文名稱 磷酸化T淋巴細胞轉錄調節因子TFEB抗體
別    名 TFEB(phospho-Ser142); TFEB(phospho-S142); TFEB(phospho Ser142); p-TFEB(Ser142); alpha TFEB; alphaTFEB; bHLHe35; T cell transcription factor EB; T-cell transcription factor EB; TCFEB; Transcription factor EB; TFEB_HUMAN.  
Specific References  (2)     |     bs-22337R has been referenced in 2 publications.
[IF=6.59] Dan Zhang. et al. Fagopyrum dibotrys extract alleviates hepatic steatosis and insulin resistance, and alters autophagy and gut microbiota diversity in mouse models of high-fat diet-induced non-alcoholic fatty liver disease. FRONT NUTR. 2022; 9: 993501  WB ;  Mouse.  
[IF=3.412] Hao Yu. et al. Activation of Transcription Factor EB Is Associated With Adipose Tissue Lipolysis in Dairy Cows With Subclinical Ketosis. Front Vet Sci. 2022; 9: 816064  WB ;  Cow(Calve).  
研究領域 細胞生物  免疫學  轉錄調節因子  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 52 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human TFEB around the phosphorylation site of Ser142: PN(p-S)PM 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Transcription factors of the basic helix-loop-helix zipper (bHLH-ZIP) family contain a basic domain, used for DNA binding, and HLH and ZIP domains, both used for oligomerization. TFEB was isolated from a human B-cell cDNA library using a binding sequence from the adenovirus major late promoter. This transcription factor probably binds to the USF/MLTF site and probably recognizes E-box sequences in the heavy-chain immunoglobulin enhancer.

Function:
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.

Subunit:
Homodimer and heterodimer; with TFE3 or MITF.

Subcellular Location:
Cytoplasm. Nucleus. Note=Mainly present in the cytoplasm. Under aberrant lysosomal storage conditions, it translocates from the cytoplasm to the nucleus.

Post-translational modifications:
Sumoylated; does not affect dimerization with MITF.

Similarity:
Belongs to the MiT/TFE family.
Contains 1 basic helix-loop-helix (bHLH) domain.

SWISS:
P19484

Gene ID:
7942

Database links:

Entrez Gene: 7942 Human

Entrez Gene: 510032 Cow

Entrez Gene: 609046 Dog

Entrez Gene: 21425 Mouse

Entrez Gene: 100157940 Pig

Entrez Gene: 316214 Rat

Omim: 600744 Human

SwissProt: P19484 Human

SwissProt: Q9R210 Mouse

Unigene: 485360 Human

Unigene: 715310 Human

Unigene: 2305 Mouse

Unigene: 22098 Rat



產品圖片
Sample: Pancreas (Mouse) Lysate at 40 ug Primary: Anti- Phospho-TFEB(Ser142) (bs-22337R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD
Sample: Lymph node(Mouse) Lysate at 40 ug Primary: Anti- Phospho-TFEB(Ser142) (bs-22337R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 一及黄色片 | 国内毛片毛片毛片毛片毛片毛片 | 色噜噜噜噜噜噜亚洲精品 | 久色88 | 国产精品99久久不卡二区 | 亚洲午夜精品一区二区三区 | 成人午夜片av在线看 | 国产AV午夜精品一区二区入口 | 91天天爽 | 精品精品国产高清a毛片 | 人av在线 | 成人性生交大片100部 | 免费观看黄页网站 | 91精品国产综合久久久久久蜜月 | 宅男一区| 天美av一区二区三区久久 | 久久婷婷五月综合色丁香 | 亚洲VS成人无码人在线观看堂 | 最新大地资源网在线观看免费 | 日本拍拍免费观看片成人 | 久久不见久久见www免费视频 | 天天爽天天狠久久久综合麻豆 | 国产一区二区久久 | 99精品国产在热久久无毒不卡 | 97久久欧美国产亚洲 | 欧美国产视频 | 欧美一区二区在线刺激视频 | 成人免费在线观看网站 | 国产一区二区不卡在线 | 日本一区精品 | 国产欧美一区二区在线 | 中文字幕一区二区三区视频 | 亚洲三区在线观看无套内射 | 欧美成人自拍 | 天堂VA视频一区二区 | 国产a篇 | 在线观看欧美一区 | 三级毛毛片 | 日韩色综合 | 日韩亚洲国产中文字幕欧美 | 国模无码视频一区 |