97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
久久国产精品一区二区三区四区,1515hhcom四虎免费观看,看看黄色毛片
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
MMP12 Recombinant Rabbit mAb (bsm-52292R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包裝/詢價

產(chǎn)品編號 bsm-52292R
英文名稱 MMP12 Recombinant Rabbit mAb
中文名稱 基質(zhì)金屬蛋白酶-12重組兔單抗
別    名 matrix metalloproteinase 12; MMP12; EC 3.4.24.65; HME; Macrophage elastase; Macrophage metaloelastase; Matrix metalloprotease 12; ME; MGC138506; MME; MMP 12; MMP12_HUMAN; MMP 12; MMP-12; MMP12.  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 1A4
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:1000-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42 kDa
檢測分子量
細(xì)胞定位 細(xì)胞外基質(zhì) 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 A synthesized peptide derived from human MMP12: 405-470 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis, metastasis, and atherosclerosis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
MMP12 was first described in murine macrophages, later in human macrophages, and more recently in other cell types. Also known as metalloelastase, MMP12 is able to degrade elastin, entactin, laminin 1, fibronectin, type IV collagen as well as insulin B-chain and casein. MMP12 is often confused with the Serine proteinase, Leukocyte elastase (EC 3.4.21.37) because of similar nomenclature. MMP12 is structurally similar to the classical MMPs (MMP1, MMP3); it contains a propeptide with autoinhibitory cysteine switch site, a well-conserved zinc site, hinge region and hemopexin domain. MMP12 lacks a transmembrane domain and furin cleavage site. The zymogen for MMP-12 is about 54 kD, and is quickly activated to the 45 kD form; and this breaks down to cascade of active forms, ending with the common 22 kD form. Stimulated macrophages produce MMP12; it has also been found in osteosarcoma cells, synovial fibroblasts and lung fibroblasts.

Subcellular Location:
Secreted, extracellular space, extracellular matrix (Probable).

Tissue Specificity:
Found in alveolar macrophages but not in peripheral blood monocytes.

Similarity:
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains.

SWISS:
P39900

Gene ID:
4321

Database links:

Entrez Gene: 4321 Human

Entrez Gene: 17381 Mouse

Entrez Gene: 117033 Rat

Omim: 601046 Human

SwissProt: P39900 Human

SwissProt: P34960 Mouse

SwissProt: Q63341 Rat

Unigene: 1695 Human

Unigene: 2055 Mouse

Unigene: 33193 Rat



產(chǎn)品圖片
25 ug total protein per lane of various lysates (see on figure) probed with MMP12 monoclonal antibody, unconjugated (bsm-52292R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP12 Monoclonal Antibody, Unconjugated(bsm-52292R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP12 Monoclonal Antibody, Unconjugated(bsm-52292R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Esophagus Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP12 Monoclonal Antibody, Unconjugated(bsm-52292R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Breast Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP12 Monoclonal Antibody, Unconjugated(bsm-52292R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP12 Monoclonal Antibody, Unconjugated(bsm-52292R) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 97少妇无码视频在线播放 | 91精品一区二区三区综合在线爱 | 狠狠操操 | 人人插97 | 国产日本欧美视频 | 日本高清视频一区二区三区四区 | 久久精品99久久 | 国产午夜福利视频在线观看 | 日韩欧美精品在线视频 | 99久e精品热线免费 狠狠躁夜夜a产精品视频 | 国产高清一区二区三区视频 | 日本正能量不良网站 | 男人日女人逼的视频 | 一本加勒比波多野结衣高清 | 免费无码AV一区二区 | 日日碰狠狠添天天爽超碰97久久 | 午夜成人影视 | 一区二区三区视频免费视频观看网站 | 91污在线观看 | 午夜三级A三级三点窝 | a级毛片高清免费视频就 | 久久99精品久久久久久久久久 | 在线不卡欧美精品一区二区三区 | 国产精品综合在线观看 | 99re6这里有精品热视频在线 | 日韩三级免费 | 国产剧情无码播放在线观看 | 日本看片一区二区三区高清 | 韩国日本三级在线 | 99精品国产99久久久久久 | av国产精品 | 国产妇女乱码一区二区三区 | 狠狠色丁香六月色 | 91女神在线视频 | 9797色 | 少妇无码一区二区三区 | 日韩视频一区二区在线 | 欧美多人乱大交xxxxx | 欧美黑人又粗又大久久久 | 91popn国产在线 | 亚洲乱码日产精品bd在线观看 |