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Recombinant human IL-28A protein (Active, HEK293) (bs-48008P)  
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產品編號 bs-48008P
英文名稱 Recombinant human IL-28A protein (Active, HEK293)
中文名稱 重組人白介素28A (活性的, Tag free)
別    名 rhIL-28A; Interleukin 28/Interferon lambda-2; Interleukin 28A; IL28A; IFNL2; IL-28A; rhIL-28A; EG330496; Ifnl2; IFNL2_HUMAN. ;Recombinant human IL-28A protein (Active, HEK293)  人白介素28A 重組蛋白; 人白細胞介素28A ; 重組人白介素28A;
克 隆 號
理論分子量 24 kDa
檢測分子量 17-38
性    狀 Lyophilized
濃    度 >0.5 mg/ml
物    種 Human
序    列 26-200/200
純    度 >95% as determined by SDS-PAGE
純化方法 AC
內毒素 <0.5 EU/μg as determined by LAL.
表達系統 HEK293 cell
活性 Yes
標簽 Tag free
緩 沖 液 Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.
保存條件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after r
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 IL-28A, also named interferon λ2 (IFNλ2), belongs to the type III interferon protein family, which is distinct from the type I IFNs. IL-28A is induced by virus infection or double stranded RNA. IL-28A acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. IL-28A has antiviral, antitumour and immunomodulatory activities, plays a critical role in the antiviral host defense, predominantly in the epithelial tissues.

This recombinant human IL-28A is produced by human cells.(Tag free)

Biological activity:
The activity was measured by its anti-virus function in A549 cells (human lung adenocarcinoma epithelial cell line) infected with encephalomyocarditis (EMC) virus.

Reconstitution:
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.



產品圖片
The purity of the protein is greater than 95% as determined by reduced and non reduced SDS-PAGE
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