97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
欧美精品一级在线观看,91黄色在线观看,999精品在线视频
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
CD20 Rabbit pAb (bs-25072R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-25072R
英文名稱 CD20 Rabbit pAb
中文名稱 CD20抗體
別    名 CD20_HUMAN; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; MS4A1; MS4A2; B1; CVID5; LEU-16; S7.  
研究領域 腫瘤  免疫學  干細胞  細胞表面分子  細胞類型標志物  淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD20: 121-220/297 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit.

Function:
This protein may be involved in the regulation of B-cell activation and proliferation

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed on B-cells.

Post-translational modifications:
Phosphorylated. Might be functionally regulated by protein kinase(s).

DISEASE:
Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.

Similarity:
Belongs to the MS4A family.

SWISS:
P11836

Gene ID:
931

Database links:

Entrez Gene: 931 Human

Omim: 112210 Human

SwissProt: P11836 Human

Unigene: 712553 Human



[PHARMACEUTICAL] Monoclonal antibodies (mAb) against CD20 are used to treat B-cell non-Hodgkin lymphoma (NHL). These antibodies include Rituximab (Mabthera), Britumomab (Zevalin) and Tositumomab (Bexxar). CD20 engaged by mAb can generate transmembrane signals capable of directly controlling cell growth and triggering cell death in certain tumors. Alternatively, mAb can mediate complement-dependent cytotoxicity. B淋巴細胞標志物 CD20是B細胞特異性抗原,其表達呈細胞類型一種質膜蛋白質,參與信號傳導作用,此抗體識別大多數(shù)B細胞上的一種抗原。多用于標記B淋巴細胞及B細胞淋巴瘤。 CD20一般不與T細胞交叉反應,對B細胞淋巴瘤和急慢性淋巴細胞白血病等有較好的細胞特異性,因此在惡性淋巴瘤,尤其是T或B細胞淋巴瘤的分類上,CD20是最常用的B細胞標志。
產(chǎn)品圖片
Sample: Lane 1: Human Raji cell lysates Lane 2: Human Ramos cell lysates Primary: Anti-CD20 (bs-25072R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 33 kDa Observed band size: 45 kDa
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产精品乱码久久久久 | 婷婷亚洲综合小说图片 | 日韩新片在线观看 | 亚洲精品久久久久中文字幕 | 欧美XXXXX高潮喷水麻豆 | 国产乱码久久 | 古典武侠激情亚洲精品一区 | 麻豆视频网页 | 免费人成视频网站在线18 | 在线观看欧美日韩国产 | 中国xxxxxxxxx88 | 成人片段大有上在线观看 | 亚洲影视网 | 国产精品视频色 | 精品视频免费播放 | 精品人妻无码专区在中文字幕 | 青青草视频精品 | 成人天堂网 | 人妻夫の上司犯感との中文字幕 | 中国视频一区二区 | 成人黄色片在线观看 | 精品无码成人片一区二区 | 最新国产の精品合集bt伙计 | 在线观看av每日更新免费 | 亚洲精品国产精品久久99 | 日夜夜操| 99激情网| 国产精品无码AV不卡 | 丰满人妻跪趴高撅肥臀 | 黄色A级国产免费大片 | 91精品国产自产在线观看自播 | 久热精品视频在线 | 台湾性色hd性色av | 欧美一级淫片免费视频欧美辣图 | 亚洲免费毛片基地 | 国产激情视频网站 | A级日本乱理伦片免费入口 四虎精品免费 | 久久久久免费视频 | www.久久成人| 久操超碰 | 国产中文字幕在线播放 |