97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
欧美精品一级在线观看,91黄色在线观看,999精品在线视频
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
CD20 Rabbit pAb (bs-25072R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-25072R
英文名稱 CD20 Rabbit pAb
中文名稱 CD20抗體
別    名 CD20_HUMAN; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; MS4A1; MS4A2; B1; CVID5; LEU-16; S7.  
研究領域 腫瘤  免疫學  干細胞  細胞表面分子  細胞類型標志物  淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD20: 121-220/297 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit.

Function:
This protein may be involved in the regulation of B-cell activation and proliferation

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed on B-cells.

Post-translational modifications:
Phosphorylated. Might be functionally regulated by protein kinase(s).

DISEASE:
Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.

Similarity:
Belongs to the MS4A family.

SWISS:
P11836

Gene ID:
931

Database links:

Entrez Gene: 931 Human

Omim: 112210 Human

SwissProt: P11836 Human

Unigene: 712553 Human



[PHARMACEUTICAL] Monoclonal antibodies (mAb) against CD20 are used to treat B-cell non-Hodgkin lymphoma (NHL). These antibodies include Rituximab (Mabthera), Britumomab (Zevalin) and Tositumomab (Bexxar). CD20 engaged by mAb can generate transmembrane signals capable of directly controlling cell growth and triggering cell death in certain tumors. Alternatively, mAb can mediate complement-dependent cytotoxicity. B淋巴細胞標志物 CD20是B細胞特異性抗原,其表達呈細胞類型一種質膜蛋白質,參與信號傳導作用,此抗體識別大多數(shù)B細胞上的一種抗原。多用于標記B淋巴細胞及B細胞淋巴瘤。 CD20一般不與T細胞交叉反應,對B細胞淋巴瘤和急慢性淋巴細胞白血病等有較好的細胞特異性,因此在惡性淋巴瘤,尤其是T或B細胞淋巴瘤的分類上,CD20是最常用的B細胞標志。
產(chǎn)品圖片
Sample: Lane 1: Human Raji cell lysates Lane 2: Human Ramos cell lysates Primary: Anti-CD20 (bs-25072R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 33 kDa Observed band size: 45 kDa
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 97久久超碰成人精品网站 | 两人视频在线播放免费观看网站 | 国产九色视频在线观看 | 国产女人50精品二区毛片视涩漫 | 色婷婷av一区二区三区久久 | 97爱视频| 91精品美利坚合众国 | 午夜精品二区 | 日本午夜在线观看 | 免费看18禁止观看黄网站 | 日韩高清www | 久久国产精品成人无码网站 | 国产中文字幕在线播放 | 99精品视频69V精品视频 | 久久99精品久久久久久久久久 | 中文久久 | 日韩精品一区二区三区中文无码 | 成人特黄a级毛片免费视频 色一乱一伦一图一区二区精品 | 成年女人av | 狠狠综合久久久久综合 | 成人免费A级毛片无码 | 国产黑色丝袜流白浆视频 | 狠狠色综合欧美激情 | 精品无码国模私拍视频 | 亚洲丁香婷婷久久一区二区 | 99精品不卡一区二区三区 | 九九九九精品九九九九 | 国产精品无码午夜福利 | 色av网 | 精品少妇的一区二区三区四区 | 欧美大黑BBBBBBBBB | 翁吻乳婷婷小玲21 | h无码精品动漫尤物 | 在线免费看黄视频 | 亚洲欧美国产国产综合一区 | 91精品国产经典在线观看 | 国产AV国片偷人妻麻豆 | 99精品久久久久久久免费 | 国产精品亚洲一区二区麻豆 | 亚洲精品少妇30p | av中文字幕最新在线观看 |