| 產(chǎn)品編號(hào) | bsm-63150R |
| 英文名稱 | phospho-BTK (Y551) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化酪氨酸蛋白激酶BTK重組兔單抗 |
| 別 名 | BTK; AGMX1; AT; ATK; XLA; PSCTK1; B-cell progenitor kinase; BPK; Bruton tyrosine kinase; Tyrosine-protein kinase BTK; IMD1. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 5C12 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 76 kDa |
| 檢測(cè)分子量 | 74 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human BTK around the phosphorylation site of Y551: DE-pY-TSS(全長(zhǎng)659aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling.Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation.After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. SWISS: Q06187 Gene ID: 695 |
