| 產(chǎn)品編號(hào) | bsm-63184R |
| 英文名稱 | CDC42 Recombinant Rabbit mAb |
| 中文名稱 | 細(xì)胞分裂周期蛋白42重組兔單抗 |
| 別 名 | CDC42; CDC42Hs; G25K; TKS. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 5D7 |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200,Flow-Cyt=1:20-50,IP=1:20-50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 21 kDa |
| 檢測(cè)分子量 | 21 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human CDC42: 50-191/191 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. SWISS: P60953 Gene ID: 998 Cdc42，是細(xì)胞骨架和細(xì)胞極化的重要調(diào)節(jié)蛋白，在減數(shù)分裂和卵母細(xì)胞成熟過(guò)程中有重要的作用，尤其在細(xì)胞分化，遷移過(guò)程中起到一定的作用,目前在腫瘤研究中得到了重視。 |
