| 產(chǎn)品編號(hào) | bsm-63278R |
| 英文名稱 | phospho-Caveolin-1 (Y14) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化細(xì)胞質(zhì)膜微囊蛋白-1重組兔單抗 |
| 別 名 | BSCL3; CAV; CAV1; Caveolin1; CGL3; LCCNS; PPH3; VIP21. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 2B5 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 20 kDa |
| 檢測(cè)分子量 | 23 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Caveolin 1 around the phosphorylation site of Y14: EGHL-pY-TVPI |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. SWISS: Q03135 Gene ID: 857 信號(hào)傳導(dǎo)（Signaling Intermediates） Caveolin-1（小凹蛋白）是細(xì)胞生長(zhǎng)相關(guān)信號(hào)途徑及腫瘤發(fā)生發(fā)展過(guò)程中重要的抑制因子，Caveolae是細(xì)胞膜內(nèi)的特殊膜結(jié)構(gòu)，參與包括細(xì)胞的分子運(yùn)輸、細(xì)胞粘附和信號(hào)轉(zhuǎn)導(dǎo)在內(nèi)的多種細(xì)胞活動(dòng)。Caveolin-1是Caveolae中重要的結(jié)構(gòu)蛋白，抑制細(xì)胞生長(zhǎng)，與多種人類腫瘤發(fā)生發(fā)展相關(guān)的信號(hào)分子相互作用。Caveolin在信號(hào)轉(zhuǎn)導(dǎo)的整合中起支架蛋白的作用。Caveolin構(gòu)成了一個(gè)蛋白家族，他們是細(xì)胞質(zhì)膜中發(fā)夾樣結(jié)構(gòu)域的主要結(jié)構(gòu)成分。Ca |
