| 產(chǎn)品編號(hào) | bsm-63308R |
| 英文名稱 | Acetyl-SOD2 (K68) Recombinant Rabbit mAb |
| 中文名稱 | 乙酰化超氧化物歧化酶2（K68）重組兔單抗 |
| 別 名 | Indophenoloxidase B; IPOB; MNSOD; MVCD6; SOD2. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 5H1 |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:100-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 25 kDa |
| 檢測(cè)分子量 | 23 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human SOD2 around the acetylation site of K68: EE-(acetyl)K-YQ |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. SWISS: P04179 Gene ID: 6648 SOD2是清除線粒體氧自由基的最主要的酶類，SOD2參與促進(jìn)細(xì)胞分化和腫瘤發(fā)生。SOD2的表達(dá)缺乏與血管病變、新生兒致死、神經(jīng)退行性病變有關(guān)聯(lián)。SOD2過(guò)度表達(dá)與抵御細(xì)胞氧化損傷有關(guān)。 超氧化物歧化酶又稱(Superoxide dismutase，簡(jiǎn)稱SOD)是參與機(jī)體抗氧化（ROS，反應(yīng)性氧離子reactive oxygen species）防御機(jī)制和抵御細(xì)胞氧化損傷最重要的酶類之一， 廣泛存在于需氧生物、耐氧生物及某些厭氧微生物中，目前已知的SOD 主要分為三類，即胞質(zhì)中Cu/Zn-SOD（即SOD1 |
