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Human Arginase 1 Ready-To-Use IHC Kit (IHC0435H)  
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50T/3200.00元
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產(chǎn)品編號 IHC0435H
英文名稱 Human Arginase 1 Ready-To-Use IHC Kit
中文名稱 人精氨酸酶1即用型免疫組化試劑盒
別    名 A I; Al; ARG 1; arg1; ARGI1_HUMAN; Arginase 1; Arginase liver; Arginase type I; Arginase; liver; Arginase-1; Arginase1; Liver type arginase; Liver-type arginase; Type I arginase; AI256583; Arg-1; ARG1; PGIF  
克 隆 號
適用樣品基質(zhì) FFPE tissue
保存條件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
產(chǎn)品介紹 Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle. The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation. By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production. In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells. In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported. In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a). Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas. Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.

SWISS:
P05089

Gene ID:
383

產(chǎn)品圖片
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0435H (Human Arginase 1 IHC Kit).
Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0435H (Human Arginase 1 IHC Kit).
Immunohistochemical analysis of paraffin embedded human liver tissue slide using IHC0435H (Human Arginase 1 IHC Kit).
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