| 產(chǎn)品編號(hào) | IHC0451H |
| 英文名稱(chēng) | Human COMT Ready-To-Use IHC Kit |
| 中文名稱(chēng) | 人兒茶酚O甲基移位酶即用型免疫組化試劑盒 |
| 別 名 | Comt1; D16Wsu103e; D330014B15Rik; HEL-S-98n; Catechol O methyltransferase; Catechol O-methyltransferase; COMT; COMT_HUMAN; EC 2.1.1.6 |
| 克 隆 號(hào) | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. SWISS: P21964 Gene ID: 1312 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human prostate cancer tissue slide using IHC0451H (Human COMT IHC Kit).
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