97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
三级成人网,四虎影视免费观看高清视频,亚洲乱码国产乱码精品精大量
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-RGC32/Gold Conjugated antibody (bs-23861R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-23861R-Gold
英文名稱 Rabbit Anti-RGC32/Gold Conjugated antibody
中文名稱 膠體金標記的 補體應答基因32抗體
別    名 RGC32; Chromosome 13 open reading frame 15; KIAA0564; MGC87338; response gene to complement 32; Response gene to complement 32 protein; RGC 32; RGCC_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  免疫學  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 15kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RGC32
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
RGC32, also known as C13orf15, is a 137 amino acid protein that localizes to the cytoplasm, as well as to the nucleus and the centrosome. Expressed at high levels in kidney, pancreas and skeletal muscle and at lower levels in brain, heart and placenta, RGC32 functions to modulate the activity of cell cycle-specific kinases, thereby regulating cell cycle progression. Additionally, RGC32 may promote cell cycle arrest at the G2/M phase transition and is thought to inhibit the growth of glioma cells, possibly functioning as a tumor suppressor. Conversely, overexpression of RGC32 may promote cell replication and assist in the pathogenesis of malignancies, suggesting that RGC32 also participates in tumor transformation and progression. RGC32 activity is induced by complement activation and by p53 in response to DNA damage. Multiple isoforms of RGC32 exist as a result of alternative splicing events.

Function:
Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.

Subunit:
Interacts with SMAD3. Interacts with CDK1 and PLK1.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm ?cytoskeleton ?centrosome. Note: Cytoplasmic in unstimulated cells. Nuclear after activation by complement. Associated with the centrosome during prometaphase and metaphase.

Tissue Specificity:
Detected in brain, heart and liver (at protein level). Highly expressed in liver, skeletal muscle, kidney and pancreas. Detected at lower levels in heart, brain and placenta. Detected in aorta endothelial cells. Overexpressed in colon, breast, prostate, bladder, lung, and ovarian cancer tissues.

Database links:
Entrez Gene: 28984 Human

Omim: 610077 Human

SwissProt: Q9H4X1 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: a级高清毛片 | 超碰福利在线观看 | 91精品久久久 | 欧美顶级大胆免费视频 | 少妇毛又多又黑又大又粗 | 精品国产一区二区三区久久 | 欧美福利影院 | 精品国产免费久久久久久尖叫 | 日本亚洲a | 8x福利第一导航 | 亚洲一区在线日韩在线尤物 | 国产香蕉一区二区在线网站 | 日本高清dvd| 中文人妻无码一区二区三区 | 天操夜夜操 | 四虎永久在线精品免费AV | 国产欧美成人不卡视频 | 91精品国产经典在线观看 | 狠狠干狠狠干 | 九草视频在线观看 | 美丽姑娘免费高清观看 | 精品国产欧美日韩不卡在线观看 | 久久艹av | 国产播放啪视频免费视频 | 91国偷自产一区二区三区蜜臀 | 成人偷拍片视频在线观看 | 国产精品视频色 | 日本一区二区三区在线看 | 国产精品久久不射 | 每日更新在线观看AV | 久久久久久久久久久美女 | 日韩福利在线视频 | 亚洲欧美日韩国产综合在线 | 欧美操操操 | 综合天堂 | 一女三男做2爱A片免费 | 特黄一级视频 | 亚洲欧美在线播放 | 色悠久久久久综合网香蕉 | 国产一级做a爰片久久 | 亚洲综合图片区色 |