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Rabbit Anti-RAB3A/AP Conjugated antibody (bs-6179R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6179R-AP
英文名稱 Rabbit Anti-RAB3A/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的ras癌基因家族Rab3a抗體
別    名 Rab 3A; RAB 3A member RAS oncogene family; Rab3a; RAB3A member RAS oncogene family; RAB3A_HUMAN; RAS associated protein RAB 3A; RAS associated protein RAB3A; Ras related protein Rab 3A; Ras related protein Rab3A; Ras-related protein Rab-3A.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 免疫學  信號轉導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Danio rerio,)
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RAB3A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
RAB3A (RAB3A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB3A include Growth Hormone Deficiency, Isolated, Type Ii. Among its related pathways are Innate Immune System and Neurotransmitter Release Cycle. GO annotations related to this gene include GTP binding and protein C-terminus binding. An important paralog of this gene is RAB3C.

Function:
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.

Subunit:
Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A and RPH3AL. Interacts with the exocyst complex through SEC15. Binds SYTL4 and RIMS1. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3 (By similarity).

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).

Tissue Specificity:
Specifically expressed in brain.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

Database links:

Entrez Gene: 5864 Human

Entrez Gene: 19339 Mouse

Entrez Gene: 25531 Rat

Omim: 179490 Human

SwissProt: P20336 Human

SwissProt: P63011 Mouse

SwissProt: P63012 Rat

Unigene: 27744 Human

Unigene: 5083 Mouse

Unigene: 44409 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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