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Rabbit Anti-UEVLD/APC Conjugated antibody (bs-6287R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6287R-APC
英文名稱 Rabbit Anti-UEVLD/APC Conjugated antibody
中文名稱 APC標記的泛素結合酶E2樣蛋白抗體
別    名 ATTP; Ubiquitin-conjugating enzyme E2 variant 3; EV and lactate malate dehydrogenase domain containing protein; EV and lactate/malate dehydrogenase domain-containing protein; signaling molecule ATTP; ubiquitin conjugating enzyme E2 like; Ubiquitin conjugating enzyme E2 variant 3; Ubiquitin E2 variant and lactate/malate dehydrogenase domain containing protein; Ubiquitin-conjugating enzyme E2 variant 3; UEV 3; UEV and lactate malate dehyrogenase domains; UEV-3; UEV2 and LDH domains containing protein; UEV3; uevld; UEVLD_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  細胞周期蛋白  腫瘤細胞生物標志物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human UEVLD
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
UEV3, also known as EV and lactate/malate dehydrogenase domain-containing protein, is a 471 amino acid protein that contains one UEV (ubiquitin E2 variant) domain, which typically interacts with ubiquitin. UEV3 is thought to be a paralogue of tsg 101, a protein that exerts regulatory effects on E2 activity in cellular ubiquitination processes. With amino-terminal homology to the catalytic domain of ubiquitin-conjugating enzymes, it is thought that UEV3 may function as a negative regulator of polyubiquitination. UEV3 is expressed in various colon carcinoma cell lines, carcinomas of the uterine cervix and peripheral blood leukocytes as well as normal colon and cervical epithelium.

Subunit:
Homodimer.

Tissue Specificity:
Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes.

Similarity:
In the N-terminal section; belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.
In the C-terminal section; belongs to the LDH/MDH superfamily.
Contains 1 UEV (ubiquitin E2 variant) domain.

Database links:
 

UniProtKB/Swiss-Prot: Q8IX04.2



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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