97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
麻豆资源,欧美91av,蜜臀久久99精品久久久酒店新书
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DRES17/Gold Conjugated antibody (bs-6299R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-6299R-Gold
英文名稱 Rabbit Anti-DRES17/Gold Conjugated antibody
中文名稱 膠體金標記的乳腺癌相關蛋白DRES17抗體
別    名 DRES17; Drosophila-related expressed sequence 17; hprune; HTCD37; Prune homolog; PRUNE like protein; TcD37 homolog; PRUNE_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DRES17
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.

Function:
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.

Subunit:
Homooligomer. Able to homodimerize via its C-terminal domain. Interacts with NME1. Interacts with GSK3; at focal adhesion complexes where paxillin and vinculin are colocalized.

Subcellular Location:
Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=In some transfected cells a nuclear staining is also observed.

Tissue Specificity:
Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas.

Similarity:
Belongs to the PPase class C family. Prune subfamily.

Database links:

Entrez Gene: 58497 Human

Entrez Gene: 229589 Mouse

SwissProt: Q86TP1 Human

SwissProt: Q8BIW1 Mouse

Unigene: 728223 Human

Unigene: 14155 Mouse

Unigene: 279287 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 中文久久 | 日本一级片在线观看 | 成人午夜激情视频 | 四虎国产成人 | 凹凸18禁在线视频 | 龙珠z免费观看国语版 | 国产精品女同一区二区三区 | 久久一次 | 琪琪午夜成人理论福利片美容院 | 91大神猫先生在线观看 | 亚洲区激情区无码区日韩区 | 久久众筹精品私拍模特 | 久久国产品 | 免费观看一级特黄欧美大片 | 北条麻妃国产九九九精品视频 | 天天爽一爽 | av夜夜草| 成人三级av在线 | 国产一级黄色录像片 | 国产精品特级片 | 离异熟女不戴套456 免费操人 | ye321夜色资源最新地址 | 欧美性受ⅹ╳╳╳黑人a性爽 | 免费看av毛片多人群伦 | 亚洲VS成人无码人在线观看堂 | 亚洲国产影院av久久久久 | 国产精品一区高清 | 无码精品人妻一区二区三区涩爱 | 午夜精品久久久久久久四虎 | 色一情一乱一乱一区99av白浆 | 欧美精品一国产成人综合久久 | 国产成人久久婷婷精品流白浆 | www.久久免费视频 | 国产精品自产拍在线观看55亚洲 | 国产亚洲欧美日韩在线一区 | 国产乱对白刺激视频在线观看 | 国产福利萌白酱在线观看视频 | 高清视频在线观看免费播放 | 91精品国产综合久久久久久蜜月 | 日韩三级免费 | 丰满少妇被猛烈进出69影院 |