97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
操比av,欧美日韩无线码在线观看,第一av
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DRES17/AP Conjugated antibody (bs-6299R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6299R-AP
英文名稱 Rabbit Anti-DRES17/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的乳腺癌相關蛋白DRES17抗體
別    名 DRES17; Drosophila-related expressed sequence 17; hprune; HTCD37; Prune homolog; PRUNE like protein; TcD37 homolog; PRUNE_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DRES17
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.

Function:
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.

Subunit:
Homooligomer. Able to homodimerize via its C-terminal domain. Interacts with NME1. Interacts with GSK3; at focal adhesion complexes where paxillin and vinculin are colocalized.

Subcellular Location:
Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=In some transfected cells a nuclear staining is also observed.

Tissue Specificity:
Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas.

Similarity:
Belongs to the PPase class C family. Prune subfamily.

Database links:

Entrez Gene: 58497 Human

Entrez Gene: 229589 Mouse

SwissProt: Q86TP1 Human

SwissProt: Q8BIW1 Mouse

Unigene: 728223 Human

Unigene: 14155 Mouse

Unigene: 279287 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 寡妇张开腿让黑人捅爽 | 91老司机福利 | 99久久精品自慰喷水 | 免费观看一级特黄欧美大片 | 国产高清无码黄片亚洲大尺度视频 | 久久三级影院 | 色呦呦视频在线 | 精品日本一区二区三区免费 | 不卡一区二区三区视频 | 国精产品一码一码三MBA | 51国产偷自视频区视频免费的 | 好爽好大久久久级淫片毛片小说 | 精品无码AV无码专区 | 国产精品视频色 | 久久精品国产亚洲av麻豆小说 | 日韩精品视频在线观看视频 | 天天综合网页在线观看 | 4438五月综合 | 国产成人午夜片在线观看高清观看 | 91九色论坛 | 国产精品久久久亚洲女人 | 九九夜夜| 欧美a级片免费观看 | 久草在线色站 | 国产在线视频不卡一区二区 | 日本在线免费 | 成人软件在线观看 | 无码日韩精品一区二区免费 | 97SE亚洲国产综合自在线 | 日本视频免费 | 午夜a级毛片免费观看 | 欧美性受ⅹ╳╳╳黑人a性爽 | 精品熟女碰碰人人A久久 | 国产极品女主播国产区 | 日韩国产一级片 | 国产女教师高潮叫床视频网站 | 国产成人精品一区一区一区 | 免费在线视频一区 | 日本黄网免费一区二区精品 | 精品一区亚洲 | 精品国产99久久久久久 |