97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
黑鬼吊太大少妇尖叫,oldgraanny日本老熟妇,国产精成人品在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DRES17/PE Conjugated antibody (bs-6299R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6299R-PE
英文名稱 Rabbit Anti-DRES17/PE Conjugated antibody
中文名稱 PE標記的乳腺癌相關蛋白DRES17抗體
別    名 DRES17; Drosophila-related expressed sequence 17; hprune; HTCD37; Prune homolog; PRUNE like protein; TcD37 homolog; PRUNE_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DRES17
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.

Function:
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.

Subunit:
Homooligomer. Able to homodimerize via its C-terminal domain. Interacts with NME1. Interacts with GSK3; at focal adhesion complexes where paxillin and vinculin are colocalized.

Subcellular Location:
Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=In some transfected cells a nuclear staining is also observed.

Tissue Specificity:
Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas.

Similarity:
Belongs to the PPase class C family. Prune subfamily.

Database links:

Entrez Gene: 58497 Human

Entrez Gene: 229589 Mouse

SwissProt: Q86TP1 Human

SwissProt: Q8BIW1 Mouse

Unigene: 728223 Human

Unigene: 14155 Mouse

Unigene: 279287 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 美女大胆作爱全过程 | 久久狠狠中文字幕2017 | 不卡av中文字幕手机看 | 天地争霸美猴王国语在线观看免费 | 97免费视频在线观看 | 亚洲欧美国产精品久久久久 | 日本亚洲a | 好紧好湿好爽免费视频在线观看 | 992tv国产精品福利在线 | 99超碰在线人人 | 国产人妻精品无码AV在线 | 2023国产亚洲精品色爽无码 | 高清免费av | 最近更新中文字幕手机版 | 9久9久女女热精品视频在线观看 | 国产免费视屏 | 日韩黄色在线播放 | 成人综合婷婷国产精品久久蜜臀 | 亚洲av中文无码字幕色最 | 国产丝袜一区视频在线观看 | 91桃色在线 | 免费追剧网址 | 逼自拍偷拍自拍天堂偷拍 | www.99日本精品片com | 欧美综合一区二区 | 亚洲日韩亚洲另类激情文学 | 青青网视频 | 蜜臀久久精品久久久久久酒店? | 欧美交换配乱吟粗大 | 欧美网站大全在线观看 | 91丨九色丨黑人外教 | 新四虎影院 | 插插无码视频大全不卡网站 | 精品国产麻豆一区二区三区 | 国产91在线播放 | 2017最新高清无码网站 | 精品成人一区二区三区四区 | 扒开双腿猛进入喷水高潮视频 | 欧美日韩免费大片 | 免费国产一区二区 | 无码免费毛片手机在线 |