97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
欧美xxxx做受欧美,日本网站黄色,国模少妇无码一区二区三区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DRES17/PE-Cy7 Conjugated antibody (bs-6299R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6299R-PE-Cy7
英文名稱 Rabbit Anti-DRES17/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的乳腺癌相關蛋白DRES17抗體
別    名 DRES17; Drosophila-related expressed sequence 17; hprune; HTCD37; Prune homolog; PRUNE like protein; TcD37 homolog; PRUNE_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DRES17
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.

Function:
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.

Subunit:
Homooligomer. Able to homodimerize via its C-terminal domain. Interacts with NME1. Interacts with GSK3; at focal adhesion complexes where paxillin and vinculin are colocalized.

Subcellular Location:
Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=In some transfected cells a nuclear staining is also observed.

Tissue Specificity:
Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas.

Similarity:
Belongs to the PPase class C family. Prune subfamily.

Database links:

Entrez Gene: 58497 Human

Entrez Gene: 229589 Mouse

SwissProt: Q86TP1 Human

SwissProt: Q8BIW1 Mouse

Unigene: 728223 Human

Unigene: 14155 Mouse

Unigene: 279287 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产在线视频福利 | 国产成人啪精品午夜网站a片免费 | 欧美最厉害的喷水VIDEOS | 国内精品久久久久影院免费 | 欧美中文字幕第一页 | 国产乱视频在线观看 | 欧美三级视频日日操 | 蜜芽国产成人精品区 | 啊灬啊灬啊灬快灬深高潮了 | 成人A片产无码免费奶头 | 女人看片www.8888成人 | 99re8这里有精品热视频8在线 | 久久精选 | 爱情岛论坛自拍亚洲品质极速福利 | 永久免费无码国产 | 色一情一乱一伦一区二区三区 | 91视频日韩 | 亚洲精品一区二区三区中文字幕 | 啦啦啦资源视频在线完整免费高清 | 5060网午夜| 男同男性xx视频在线观看免费 | 伊人75在线| 97国产情侣爱久久免费观看 | 91精品国产9 | a黄在线观看 | 成在人线AV无码免费高潮喷水 | 成人午夜做爰视频免费看 | 最近日本MV字幕免费观看 | 亚洲国产精品一区二区久 | 国产99久久亚洲综合精品西瓜tv | 亚洲av无码久久寂寞少妇 | 91精品国产91久久 | 中国一级黄色片 | 免费看奶头视频的网站 | 国外精品久久久蜜桃免费全文阅读 | 成年日韩片AV在线网站医生 | 日本少妇激三级做爰在线 | 狠狠婷婷| 欧美伊人久久 | 玩弄人妻奶水无码av在线 | 亚洲国产亚洲 |